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  • B6;129P2-Gt(ROSA)26Sortm1(CAG-ALPP)Fawa/J

    产品型号:GM-J#010523 -Cryorecovery

    产品应用:These mice contain (STOP-hPLAP): the human alkaline phosphatase, placental (Regan isozyme), ALPP, gene under the control of the CAG (chicken beta actin promoter/enhancer and cytomegalovirus immediate-early enhancer) promoter, inserted into the Gt(ROSA)26Sor locus. Expression of the ALPP gene is blocked by a loxP-flanked STOP fragment placed between the ALPP sequence and the Gt(ROSA)26Sor promoter. This strain serves as a reporter strain, with successful Cre-mediated excision being indicated by ALPP expression in cre-expressing tissues.

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