产品型号：GM-J#010557 -Cryorecovery

产品应用：These R26rtTACreER mice have a CreERT, reverse tetracycline trans-activator (rtTA), and Tet-responsive element (TRE) targeted to the mouse Gt(ROSA)26Sor gene to create a gene expression tool with two independent layers of pharmacologic control and a widespread pattern of activity. In this construct, expression of tamoxifen-sensitive CreERT is under the control of rtTA. Upon administration of doxycycline, rtTA activates transcription of the CreER coding region. This enhances the dynamic range of CreER and enables sparse labeling in situations where reduced recombination efficiency facilitates behavioral, morphological or functional studies of modified cells among populations of unmodified neighbors.