型号：GM-J#016879 -Not Available At Jax

应用：In 2022, a SNP panel was run on this strain and it was discovered that this line has been maintained on a C57BL/6J congenic background. This strain will now be offered as Stock No. 035717.

型号：GM-J#016849 -Available

应用：These floxed mutant mice contain loxP sites flanking exons 2-3 of the Ccl2 gene which has been modified with a red fluorescent protein gene (mcherry). Fluorescence is seen in all Ccl2-expressing cells. When these mutant mice are bred to mice that express Cre recombinase, resulting offspring will have exons 2-3, as well as RFP, deleted in the cre-expressing tissue.

型号：GM-J#016833 -Cryorecovery

应用：The Alb1-cre transgene was designed with a Cre recombinase gene under control of Alb promoter/enhancer elements. These mice may be useful for studying the liver specific deletion of target genes.

型号：GM-J#016832 -Cryorecovery

应用：The Alb1-cre transgene was designed with a Cre recombinase gene under control of Alb promoter/enhancer elements. These mice may be useful for studying the liver specific deletion of target genes.

型号：GM-J#016829 -Cryorecovery

应用：These knock-in mice (also referred to as Oct4-MerCreMer mice) express a tamoxifen-inducible cre recombinase from the endogenous promoter/enhancer elements of the Pou5f1 gene. When induced, cre activity is observed in Pou5f1 expressing cells in embryos and in Induced pluripotent stem (iPS) cells derived from these mice. These mice may be useful for generating conditional mutations for studying lineage tracing, and production of cell lines and targeted knock-out mutations.

型号：GM-J#016617 -Available

应用：The Cre recombinase/green fluorescent protein fusion protein, driven by the Nr4a1 (Nur77) promoter in these mice, is expressed mainly in a subset of myeloid lineage cells of the spleen. These mice may be useful in studying thymocyte positive- and negative-selection as well as lymphocyte activation.

型号：GM-J#016584 -Cryorecovery

应用：These TPH2-iCreER transgenic mice express a tamoxifen-inducible Cre recombinase under the control of the mouse Tph2 promoter and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping of Tph2 expressing neurons in the raphe nucleus.

型号：GM-J#016583 -Cryorecovery

应用：These DAT-iCreER transgenic mice express a tamoxifen-inducible Cre recombinase under the control of the mouse Slc6a3 promoter region and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping of dopaminergic neurons in the substantia nigra and locus coeruleus, as well for studying drug addiction, Parkinson's disease and Attention Deficit-Hyperactivity Disorder (ADHD).

型号：GM-J#016582 -Cryorecovery

应用：These VGAT-iCreER transgenic mice express a tamoxifen-inducible Cre recombinase under the control of the mouse Slc32a1 promoter region and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping throughout the brain in neurons that structurally resemble interneurons.

型号：GM-J#016576 -Cryorecovery

应用：R1441C-LRRK2 transgenic mice have a minimal cytomegalovirus (CMV) enhancer and human platelet derived growth factor, B polypeptide (PDGFB) promoter/enhancer elements driving expression of a mutated full length human leucine-rich repeat kinase 2 (LRRK2*R1441C) cDNA. These mice may be useful for studying Parkinson's disease pathogenesis and neurodegeneration elicited by the dominant toxic effects of mutant LRRK2*R1441G expression.