型号：GM-J#017490 -Cryorecovery

应用：These Stra8-cre transgenic mice have expression of Cre recombinase (iCre) directed by the Stra8 genomic promoter fragment, and may be useful in generating conditional knockouts in postnatal, premeiotic, male germ cells for studying spermatogenesis.

型号：GM-J#017457 -Cryorecovery

应用：These transgenic mice carry both an mCherry fluorescent gene flanked by loxP sites and the yeast transcription activator protein GAL4 under the control of a cytomegalovirus enhancer/beta actin promoter (CAG). This strain may be effectively used as a component of the GAL4-UAS (Upstream Activation Sequence) system to activate gene transcription.

型号：GM-J#017456 -Cryorecovery

应用：These transgenic mice carry both an mCherry fluorescent gene flanked by loxP sites and the yeast transcription activator protein GAL4 under the control of a cytomegalovirus enhancer/beta actin promoter (CAG). This strain may be effectively used as a component of the GAL4-UAS (Upstream Activation Sequence) system to activate gene transcription.

型号：GM-J#017455 -Cryorecovery

应用：The R26-CAG-LSL-2XChETA-tdTomato reporter allele is designed to express two individual proteins following exposure to Cre recombinase; the ChR2-E123T accelerated (ChETA)/H134R variant of channelrhodopsin-2 and tdTomato fluorescent protein gene. When used with neuron-specific Cre recombinase expressing strains, the double mutant mice can be used in optogenetic studies and visualization of whole neurons.

型号：GM-J#017353 -Cryorecovery

应用：Expression of the YFP-Cre fusion gene in these mice is observed in Il13-expressing cells, including innate type 2 helper cells. These YetCre-13 mice may be useful for fluorescent reporter and/or Cre-lox studies of IL-13-expressing cells in type 2 immunity/host response to allergens and parasitic helminths.

型号：GM-J#017346 -Cryorecovery

应用：These A930038C07Rik-Tg1-Cre mice express Cre recombinase under the control of the A930038C07Rik (RIKEN cDNA A930038C07 gene [also called epidermacan]) promoter/enhancer regions within the BAC transgene. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues; specifically in neocortical deep layer 5 (Layer 5B) cells/thick-tufted pyramidal neurons of adult mice.

型号：GM-J#017336 -Available

应用：CD4-Cre transgenic mice contain CD4 enhancer, promoter and silencer sequences driving the expression of a Cre recombinase gene. These mice may be useful for generating conditional mutations in CD4-expressing tissues.

型号：GM-J#017320 -Available Now

应用：PV-Cre knock-in (Pvalb-IRES-Cre) mice express Cre recombinase in parvalbumin-expressing neurons (such as interneurons in the brain and proprioceptive afferent sensory neurons in the dorsal root ganglia), without disrupting endogenous Pvalb expression. These mice may be useful in studying neuronal development, differentiation, and physiology.

型号：GM-J#017310 -Cryorecovery

应用：Mice hemizygous for the BAC Hsd17b1-icreERT2 transgene are viable, fertile, and normal in size with iCre-ERT2 expression directed by the hydroxysteroid (17-beta) dehydrogenase 1 (Hsd17b1) promoter/enhancer regions within the BAC transgene. These mice may be useful for studying gene function in ovarian granulose cells.

型号：GM-J#017009 -Available Now

应用：Nfe2l2tm1Ywk (NRF2) knockout mice may be useful for studying oxidative stress in the pathogenesis of age-related macular degeneration, diabetes, Parkinson's disease, and other inflammatory degenerative diseases as well as studies of cancer, multiple sclerosis, liver cirrhosis, atherosclerosis, injury and wound healing, and more.