型号：GM-J#018448 -Cryorecovery

应用：This Foxn1ex9cre strain expresses Cre recombinase from the endogenous Foxn1 (forkhead box N1) locus without disruption of the Foxn1 coding sequence. When crossed with a strain containing loxP site-flanked sequence, Cre-mediated recombination results in deletion of the flanked region in thymic epithelial cells and keratinocytes.

型号：GM-J#018442 -Cryorecovery

应用：These SNCA-Wt mice express a wild-type human synuclein, alpha (non A4 component of amyloid precursor), SNCA, gene directed by the human SNCA promoter/enhancer regions on the BAC transgene. These mice may be useful for studying SNCA function and the pathogenesis of Parkinson's disease.

型号：GM-J#018439 -Cryorecovery

应用：These Tg hSMN2 E9 inducible SMN transgenic mice conditionally express a human SMN2 cDNA. Widespread lacZ expression is observed except in those tissues where cre recombination has resulted in the human SMN2 cDNA to be expressed instead. These transgenic mice are suitable for use in studies related to Spinal Muscular Atrophy.

型号：GM-J#018422 -Cryorecovery

应用：These AID-Cre mice may be useful for fate mapping of B cells originating in the follicular germinal centers of the spleen and lymph nodes.

型号：GM-J#018418 -Cryorecovery

应用：In this strain Cre-ERT2 is knocked into the translational start site of the Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1) gene. This strain may be useful for mediating inducible cre recombination in Lrig1 expressing tissues, and for applications in lineage mapping proliferative and quiescent intestinal progenitor cells.

型号：GM-J#018394 -Cryorecovery

应用：K5-Cre-ERT2 transgenic mice express tamoxifen-inducible Cre recombinase under the direction of the bovine keratin 5 (KRT5) promoter/enhancer regions. They are useful for applications requiring tamoxifen-induced deletion of floxed sequences in epithelial cells.

型号：GM-J#018385 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#018280 -Available

应用：Pdgfra-creERTM transgenic mice can be used to create conditional mutations in oligodendrocyte precursor or NG2+ cells in the adult forebrain and spinal cord. They may have applications in studies related to CNS cell repair and replacement.

型号：GM-J#018147 -Cryorecovery

应用：iCre recombinase expression is evident in interneurons of the brain and in amacrine cells of the inner retina.

型号：GM-J#018142 -Cryorecovery

应用：This Igs1 (intergenic site 1, formerly Ubb) knock-in strain gives constitutive expression of a nuclear localized beta-galactosidase/neomycin resistance protein reporter (NLS-beta-geo) in the absence of cre-mediated recombination. Following cre-mediated recombination, the NLS-beta-geo coding region is excised and Wnt11 is expressed.