型号:GM-J#018968 -Cryorecovery
应用:Vav-iCre transgenic mice have the mouse HS21/45 control regions directing expression of an optimized variant of Cre recombinase (iCre) to hematopoietic cells (and their progenitors), and may be useful for generating conditional mutations in hematopoietic cells.
型号:GM-J#018967 -Cryorecovery
应用:Mice harboring the Itgax-cre (Cd11c-Cre) BAC transgene express Cre recombinase under control of the integrin alpha X gene (Itgax or Cd11c) promoter/enhancer regions within the BAC transgene. These Cd11c-Cre transgenic mice are a Cre-lox tool for deletion of floxed sequences in CD8-, CD8+ dendritic cells, tissue-derived dendritic cells from lymph nodes, lung and epidermis, as well as plasmacytoid dendritic cells. This strain may be useful for studying dendritic cell homeostasis and function.
型号:GM-J#018966 -Cryorecovery
应用:These CaMKIIalpha-cre T29-1 transgenic mice have the mouse calcium/calmodulin-dependent protein kinase II alpha (Camk2a) promoter driving Cre recombinase expression in the forebrain, specifically to the CA1 pyramidal cell layer in the hippocampus.
型号:GM-J#018965 -Cryorecovery
应用:The FABP4-Cre transgene has a 5.4 kbp mouse Fabp4 promoter directing expression of Cre recombinase. These FABP4-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in brown and white adipose tissue.
型号:GM-J#018964 -Available
应用:The K14-Cre transgene has a human keratin 14 promoter directing expression of Cre recombinase. These K14-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in the ectoderm and its derivatives (including the skin, dental epithelium, and oral ectoderm).
型号:GM-J#018963 -Cryorecovery
应用:These Vil1-cre mice express Cre recombinase in villus and crypt epithelial cells of the small and large intestines and may be useful in studies of intestinal organogenesis. In contrast to Villin-cre transgenic mice from founder line 1000 (Stock No. 021504) that are reported be absent of Cre recombinase activity in gonads, these Villin-cre transgenic mice from founder line 997 are reported to have a very low level (<1%) of cells with Cre recombinase activity in the testes.
型号:GM-J#018961 -Cryorecovery
应用:Alb-cre transgenic mice are useful for deletion of loxP-flanked genes in the liver.
型号:GM-J#018960 -Cryorecovery
应用:The RIP-Cre transgene has a 668 bp fragment of the rat insulin II promoter, nuclear-localized Cre recombinase, and a 2.1 kbp fragment from the human growth hormone gene. These RIP-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in pancreatic beta cells.
型号:GM-J#018958 -Cryorecovery
应用:The CD19-Cre knockin/knockout allele has a Cre recombinase gene inserted into the first coding exon of the CD19 antigen gene (Cd19); both abolishing endogenous Cd19 gene function and placing cre expression under the control of the endogenous Cd19 promoter/enhancer elements. Cre recombinase
型号:GM-J#018957 -Cryorecovery
应用:ChAT-IRES-Cre knock-in mice express Cre recombinase in cholinergic neurons, without disrupting endogenous Chat expression. These mice may be useful in neurobiological research of motor function, learning and memory, Alzheimer's disease, and Down syndrome, as well as obesity and diabetes research.