型号:GM-J#018956 -Cryorecovery
应用:The LysMcre knock-in/knockout allele has a nuclear-localized Cre recombinase inserted into the first coding ATG of the lysozyme 2 gene (Lyz2); both abolishing endogenous Lyz2 gene function and placing NLS-Cre expression under the control of the endogenous Lyz2 promoter/enhancer elements. These LysMcre mice may be useful for Cre-lox studies of the myeloid cell lineage (monocytes, mature macrophages and granulocytes) and the innate immune response.
型号:GM-J#018938 -Cryorecovery
应用:Tac2-Cre knock-in/knockout mice have endogenous gene expression abolished and Cre recombinase expression directed to Tac2-expressing cells by the endogenous promoter/enhancer elements of the tachykinin 2 locus. These mice may be useful to generate conditional mutations for studying gain or loss of function and/or mapping in dorsal root ganglia, the dorsal horn of the spinal cord, and parts of the brain.
型号:GM-J#018937 -Cryorecovery
应用:This strain is useful for permanent labeling of a rare and transient subpopulation of mouse embryonic stem (ES) cells that lack the typical inner cell mass pluripotency markers found in two-cell (2C) embryos but can contribute to the development of both embryonic and extraembryonic tissues.
型号:GM-J#018903 -Cryorecovery
应用:These R26MASTR mice express an eGFPcre fusion protein following FLP-mediated recombination, allowing simultaneous eGFP-labeling and cre-mediated deletion of floxed alleles within the same mutant cells.
型号:GM-J#018899 -Cryorecovery
应用:These Krt6-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by keratin 6 (Krt6) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.
型号:GM-J#018898 -Cryorecovery
应用:These Krt6-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by keratin 6 (Krt6) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.
型号:GM-J#018896 -Cryorecovery
应用:These Krt6-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by keratin 6 (Krt6) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.
型号:GM-J#018895 -Cryorecovery
应用:These Krt6-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by keratin 6 (Krt6) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.
型号:GM-J#018867 -Cryorecovery
应用:In this inducible Axin2 (axin2) knock-in/knockout strain, Cre-ERT2 protein expression affects cells with active Wnt/β-catenin pathway signaling. Crosses with floxed reporter strains enable conditional stem cell-specific labeling.
型号:GM-J#018829 -Cryorecovery
应用:These transgenic mice express an inducible version of cre recombinase mice under the direction of a Sox9 promoter. They are suitable for performing cre-recombination in pancreatic ductal cells and their progenitors.