型号：GM-J#017836 -Cryorecovery

应用：LGB-Cre (originally BLG-cre) transgenic mice have the beta-lactoglobulin promoter directing Cre recombinase expression to mammary gland during lactation. This strain may be useful for studying basal-like cancer and breast cancer, as well as providing a useful tool for testing new therapeutics.

型号：GM-J#017769 -Available

应用：These TRPV1Cre knock-in mice express Cre recombinase from the endogenous Trpv1 locus and may be useful for generating conditional mutations to study heat and capsaicin nociception or fate mapping of TRPV1 expression during development.

型号：GM-J#017763 -Available

应用：A CreERT2 fusion protein sequence inserted downstream of the Pax7 stop codon allows endogenous PAX7 expression in these mice while permitting specific conditional labeling, manipulation, and deletion of satellite cells.

型号：GM-J#017744 -Cryorecovery

应用：This PrPmtA transgenic strain expresses mutant human A53T alpha-synuclein (SNCA). Homozygotes may be a useful model for early stages of Parkinson's Disease, in particular to study the mechanisms of striatal synaptic plasticity, and may become a useful tool to study mechanisms of LevoDopa-induced dyskinesia.

型号：GM-J#017743 -Cryorecovery

应用：A CreERT2 fusion protein and β-galactosidase (lacZ) gene knocked into the ATG start codon of Prom1 abolishes gene function in these mice. Useful applications include visualizing and tracking adult stem cell lineages.

型号：GM-J#017738 -Cryorecovery

应用：Mice harboring the Foxl1-Cre transgene express Cre recombinase under the control of the mouse Foxl1, forkhead box L1, promoter, in the mesenchymal cells of the stomach and intestine, and in oval cells in injured liver. They may be useful for generating conditional mutations in gastrointestinal mesenchyme and liver progenitor cells.

型号：GM-J#017701 -Cryorecovery

应用：The Kiss1-CreGFP allele expresses a CreGFP fusion protein from the Kiss1 promoter/enhancer elements. These knock-in mice may be useful for visualizing KISS1 secreting neurons and for studying their role in fertility.

型号：GM-J#017682 -Available

应用：This transgenic line expresses human SNCA under the direction of a mouse Thy-1 promoter. Applications exist in studies related to Parkinson's disease and neurodegeneration elicited by the aggregation of SNCA.

型号：GM-J#017678 -Cryorecovery

应用：This double mutant strain expresses mutant human A53T alpha-synuclein (SNCA) and carries a targeted mutation for Pink1, PTEN induced putative kinase 1, and has applications in studies of the early stages of Parkinson's Disease.

型号：GM-J#017643 -Cryorecovery

应用：These 14qC3-CDRfl mice carry a floxed segment that encompasses sequence corresponding to a common deleted region (CDR) involved in most common B cell chronic lymphocytic leukemias in humans. They have applications in studies related to tumorigenesis and therapeutic management of chronic lymphocytic leukemia.