型号：GM-J#023527 -Cryorecovery

应用：The C57BL/6J-congenic Slc17a7-IRES2-Cre-D strain is available as Stock No. 037512. The B6;129S background Slc17a7-IRES2-Cre-D strain (Stock No. 023527) is available via cryo recovery.

型号：GM-J#023526 -Cryorecovery

应用：Rorb-IRES2-Cre-D knockin mice have Cre recombinase expression directed to Rorb-expressing cells, without disrupting endogenous RAR-related orphan receptor beta expression. These mice may be useful for studying this nuclear hormone receptor/DNA-binding protein in hormone-responsive gene expression and behavior.

型号：GM-J#023525 -Cryorecovery

应用：Snap25-IRES2-Cre-D knockin mice have widespread Cre recombinase expression directed throughout the brain, without disrupting endogenous synaptosomal-associated protein 25 expression. These mice may be useful for studying t-SNARE proteins and synaptic vesicle/plasma membrane fusion.

型号：GM-J#023453 -Cryorecovery

应用：These Lhx8cre/cerulean mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by the endogenous LIM homeobox protein 8 promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.

型号：GM-J#023451 -Cryorecovery

应用：These transgenic mice express human CD4 and CCR5 under the regulatory control of the human ubiquitin C promoter in combination with a widely-expressed luciferase reporter regulated by the Gt(ROSA)26Sor promoter. The mice enable the rapid measurement of HIV-1 transmission by peritoneal and genitomucosal HIV-1 pseudovirus entry in vivo. The system represents a model for the pre-clinical evaluation of prophylactic or vaccine candidates.

型号：GM-J#023428 -Cryorecovery

应用：This mouse strain features a Cre-inducible luciferase reporter gene inserted into exon 2 of the mouse Cdkn1a gene, knocking out expression. Cre-mediated excision of a floxed stop segment enables tissue-specific expression of luciferase under the direction of the endogenous Cdkn1a promoter.

型号：GM-J#023426 -Cryorecovery

应用：This Kiss1-Cre transgenic line expresses Cre recombinase in Kiss1 (kisspeptin) expressing cells and neurons and has applications in studies of the gonadotropic axis regulation and reproductive function.

型号：GM-J#023409 -Cryorecovery

应用：These mutant mice express the D620N mutation in exon 15 of the Vps35 (VPS35 retromer complex component) gene. VPS35 D620N KI mice recapitulate many of the characteristics of Parkinson's disease including neurodegeneration of DA neurons, accumulation of α-synuclein in DA neurons and age-dependent progressive motor deficits.

型号：GM-J#023407 -Cryorecovery

应用：These Creface transgenic mice have a cre-recombinase sequence driven by the human transcription factor AP-2, alpha promoter/enhancer elements, and a polyadenylation sequence followed by parts of exons 5-6 of Tfap2a, encoding the frontonasal prominence (FNP) and limb enhancer elements. This transgene integrated into intron 9 of the hedgehog acyltransferase (Hhat) gene, abolishing Hhat gene function. These mice may be useful for studying craniofacial development.

型号：GM-J#023342 -Cryorecovery

应用：These mice express muscle specific tamoxifen-inducible cre, and may be useful when evaluating embryonic muscle-specific cell lineage contributions to the adult satellite cell compartment.