型号：GM-J#033687 -Cryorecovery

应用：Sf1-Cre transgenic mice express Cre recombinase under the direction of the mouse Nr5a1 (nuclear receptor subfamily 5, group A, member 1) promoter. Cre expression is detected in steroidogenic factor-1 (SF1)-positive neurons in the ventromedial hypothalamic nucleus as well as pituitary, gonad, and adrenal tissue. These mice may be useful for generating tissue specific-targeted mutants for studies of the subset of SF1-positive neurons, obesity, metabolic and energy homeostasis, and appetite control/saeity.

型号：GM-J#033545 -Cryorecovery

应用：Rosa26PA-Cre B4 mice express a photoactivatable Cre recombinase (PA-Cre 3.0) following exposure to FLP recombinase. Specifically, FLP-mediated removal of the frt-flanked STOP cassette results in expression of the individual split Cre segments (nMag::CreN59 and pMag::CreC60). Subsequent illumination with blue-light causes nMag-pMag dimerization (Magnets-opti dimerization), which brings the split Cre segments together to form a functional Cre recombinase molecule. This allows for highly efficient DNA recombination in an internal organ of living mice through noninvasive external blue light illumination, without unintended leakiness in the dark condition.

型号：GM-J#033544 -Cryorecovery

应用：Rosa26PA-Cre A20 mice express a photoactivatable Cre recombinase (PA-Cre 3.0) following exposure to FLP recombinase. Specifically, FLP-mediated removal of the frt-flanked STOP cassette results in expression of the individual split Cre segments (nMag::CreN59 and pMag::CreC60). Subsequent illumination with blue-light causes nMag-pMag dimerization (Magnets-opti dimerization), which brings the split Cre segments together to form a functional Cre recombinase molecule. This allows for highly efficient DNA recombination in an internal organ of living mice through noninvasive external blue light illumination, without unintended leakiness in the dark condition.

型号：GM-J#033394 -Cryorecovery

应用：NtsR2Cre mice have a Cre Recombinase sequence downstream of the stop codon of the neurotensin receptor 2 (Ntsr2) gene. These mice may be useful as a reporter when studying developmental versus adult expression patterns of NtsR2.

型号：GM-J#033376 -Cryorecovery

应用：Amh-cre transgenic mice have expression of Cre recombinase directed by the testis Sertoli cell-specific promoter elements of the anti-Mullerian hormone (Amh) gene. These Amh-cre transgenic mice may be useful in generating conditional knockouts in testis Sertoli cells for studying male embryonic sexual differentiation and the regulation of spermatogenesis.

型号：GM-J#033365 -Cryorecovery

应用：NtsR1ΔNeo-Cre mice have a Cre Recombinase sequence inserted downstream of the stop codon of the neurotensin receptor 1 (Ntsr1) gene. These mice may be useful as a reporter when studying developmental versus adult expression patterns of NtsR1.

型号：GM-J#033354 -Cryorecovery

应用：Nxph4-2a-Cre knock-in mice express Cre recombinase from the mouse Nxph4 (neurexophilin 4) promoter. Cre activity recapitulates that of the endogenous Nxph4 gene in the brain. These mice may be useful in studies of study thirst, thermoregulation, and other processes regulated by neurons expressing Nxph4.

型号：GM-J#033331 -Cryorecovery

应用：Tbx4LME‐Cre mice express cre recombinase from the mouse Tbx4 (T-box 4) enhancer/Hsp68 minimal promoter, enabling targeted labeling and other genetic manipulations specifically in lung mesenchyme.

型号：GM-J#033319 -Available

应用：These CRISPR/Cas9 generated Lyve1ncre:Cx3cr1ccre (CX/Lyve1) mice use a binary transgenic Cre approach to dissect functions of central nervous system (CNS) macrophage subpopulations.

型号：GM-J#033318 -Available

应用：These CRISPR/Cas9 generated Sall1ncre:Cx3cr1ccre (CX/Sall1) mice use a binary transgenic cre approach to dissect functions of central nervous system (CNS) macrophage subpopulations.