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  • B6J.FVB(129)-Tg(Nr5a1-cre)7Lowl/R

    产品型号:GM-J#033687 -Cryorecovery

    产品应用:Sf1-Cre transgenic mice express Cre recombinase under the direction of the mouse Nr5a1 (nuclear receptor subfamily 5, group A, member 1) promoter. Cre expression is detected in steroidogenic factor-1 (SF1)-positive neurons in the ventromedial hypothalamic nucleus as well as pituitary, gonad, and adrenal tissue. These mice may be useful for generating tissue specific-targeted mutants for studies of the subset of SF1-positive neurons, obesity, metabolic and energy homeostasis, and appetite control/saeity.

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