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  • 型号:GM-J#033026 -Available

    应用:Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

    2024-11-09 点击次数:0

    型号:GM-J#033019 -Cryorecovery

    应用:Mice harboring the vil-Cre transgene have the 9-kb mouse, Vil1, villin 1, promoter directing expression of Cre recombinase to the intestinal epithelia and kidney, and may be useful for generating conditional mutations in cells of the crypt villus axis and kidney. This strain also is available on the C57BL/6J background (Stock No. 035595).

    2024-11-09 点击次数:0

    型号:GM-J#032998-JAX -Cryorecovery

    应用:In this ROSA NOTCH3-WT76 knockin strain, expression of the human NOTCH3 is blocked by an upstream loxP-flanked STOP sequence. Cre-mediated excision results in expression of human NOTCH3 and GFP targeted to the nucleus. Expression of NOTCH3 in vascular smooth muscle cells rescues the stroke susceptibility phenotype of Notch3 knockout mice.

    2024-11-09 点击次数:0

    型号:GM-J#032928-JAX -Cryorecovery

    应用:These mice have the Ple167-EGFP/NLS-cre transgene targeted as a single copy "knockin" into the upstream region of the Hprt1 locus on the X chromosome. The promoter/regulatory regions of the human POGZ gene directs expression of an enhanced green fluorescent protein/Cre recombinase fusion protein.

    2024-11-09 点击次数:0

    型号:GM-J#032926-JAX -Cryorecovery

    应用:These mice have the Ple103-EGFP/cre transgene targeted as a single copy "knockin" into the upstream region of the Hprt1 locus on the X chromosome. The promoter/regulatory regions of the human HAP1 gene direct expression of an enhanced green fluorescent protein/Cre recombinase fusion protein.

    2024-11-09 点击次数:0

    型号:GM-J#032924-JAX -Cryorecovery

    应用:These Ple177-EGFPCre;mEMS762 mice have the Ple177-EGFPCre transgene targeted as a single copy "knockin" into the upstream region of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus on the X chromosome. As the promoter/regulatory regions of the human regulator of G-protein signaling 16 (RGS16) gene direct expression of an EGFPCre fusion protein to hippocampus, thalamus, forebrain, cortex, brainstem, cerebellum, and retina, these Ple177-EGFPCre;mEMS762 mice may be useful in studying RGS16-expressing cells in the brain and diseases affecting the brain.

    2024-11-09 点击次数:0

    型号:GM-J#032923-JAX -Cryorecovery

    应用:These Ple176-EGFPCre;mEMS759 mice have the Ple176-EGFPCre transgene targeted as a single copy "knockin" into the upstream region of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus on the X chromosome. As the promoter/regulatory regions of the human regulator of G-protein signaling 16 (RGS16) gene direct expression of an EGFPCre fusion protein to hippocampus, thalamus, forebrain, cortex, brainstem, cerebellum, and retina, these Ple176-EGFPCre;mEMS759 mice may be useful in studying RGS16-expressing cells in the brain and diseases affecting the brain.

    2024-11-09 点击次数:0

    型号:GM-J#032923 -Cryorecovery

    应用:c-kitIRES-Cre mice have the endogenous Kit locus directing expression of Cre recombinase to molecular layer interneurons and Purkinje cells of the cerebellum in adult animals. These mice are useful in studies of neuron function in the adult mouse cerebellum.

    2024-11-09 点击次数:0

    型号:GM-J#032922-JAX -Cryorecovery

    应用:These Ple162-EGFPCre;mEMS954 mice have the Ple162-EGFPCre transgene targeted as a single copy "knockin" into the upstream region of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus on the X chromosome. As the promoter/regulatory regions of the human paired-like homeodomain 3 (PITX3) gene direct expression of an EGFPCre fusion protein to a discrete, non-dopaminergic cell population in the ventral midbrain that borders the fasciculus retroflexus and the dorsal edge of the main dopaminergic population of the ventral tegmental area (VTA), these Ple162-EGFPCre;mEMS954 mice may be useful in studying PITX3-expressing cells in the brain and diseases affecting the brain, including mesocorticolimbic dopamine system function in the drug and natural reward circuitry of the brain, cognition, motivation, drug addiction, and psychiatric disorders.

    2024-11-09 点击次数:0

    型号:GM-J#032921-JAX -Cryorecovery

    应用:These Ple178-EGFPCre;mEMS756 mice have the Ple178-EGFPCre transgene targeted as a single copy "knockin" into the upstream region of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus on the X chromosome. As the promoter/regulatory regions of the human regulator of G-protein signaling 16 (RGS16) gene direct expression of an EGFPCre fusion protein to hippocampus, thalamus, forebrain, cortex, brainstem, cerebellum, and retina, these Ple178-EGFPCre;mEMS756 mice may be useful in studying RGS16-expressing cells in the brain and diseases affecting the brain.

    2024-11-09 点击次数:0
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