产品型号：GM-J#033544 -Cryorecovery

产品应用：Rosa26PA-Cre A20 mice express a photoactivatable Cre recombinase (PA-Cre 3.0) following exposure to FLP recombinase. Specifically, FLP-mediated removal of the frt-flanked STOP cassette results in expression of the individual split Cre segments (nMag::CreN59 and pMag::CreC60). Subsequent illumination with blue-light causes nMag-pMag dimerization (Magnets-opti dimerization), which brings the split Cre segments together to form a functional Cre recombinase molecule. This allows for highly efficient DNA recombination in an internal organ of living mice through noninvasive external blue light illumination, without unintended leakiness in the dark condition.