型号：GM-J#036770 -Available For Registering Interest

应用：Gm5127(BAC)CreERT2 transgenic mice express a tamoxifen inducible Cre recombinase/ERT2 fusion under the control of the mouse Gm5127 promoter elements. Cre recombinase activity is observed specifically in venous endothelial cells. This strain may be useful in studies of angiogenesis, and specifically, in fate mapping of venous endothelial cells in the brain and retinal and dermal vascular in postnatal and adult mice stages.

型号：GM-J#036763 -Cryorecovery

应用：SncaNLS mice have a nuclear localization signal (NLS) and Flag tag inserted into the 3' region of the endogenous alpha synuclein gene, resulting in localization of aSyn protein to the cell nucleus. These mice exhibit age-dependent motor deficits independent of aSyn aggregation and may be useful in the study of Parkinson's Disease.

型号：GM-J#036761 -Available

应用：These LSL-h2b-GFP mice harbor a targeted mutation in the Gt(ROSA)26Sor locus with a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven enhanced green fluorescent protein (EGFP). EGFP is only expressed following cre-mediated recombination. This strain may be useful as an intersectional reporter for cre expression.

型号：GM-J#036760 -Cryorecovery

应用：These IS2 reporter mice harbor a targeted mutation of the Gt(ROSA)26Sor locus with a loxP-flanked STOP cassette and an FRT-flanked dTomato (dimer Tomato) sequence preventing transcription of a CAG promoter-driven enhanced green fluorescent protein (EGFP). dTomato is expressed following cre-mediated recombination. EGFP is only expressed following cre-mediated and Flp-mediated recombination. This strain may be useful as an intersectional reporter for cre and FLP expression, or as a subtraction reporter for cre expression alone.

型号：GM-J#036751 -Cryorecovery

应用：GfralCreERT mice have the endogenous GDNF family receptor alpha like (Gfral) promoter/enhancer sequences directing expression of tamoxifen-inducible Cre recombinase. These mice are a Cre-lox tool allowing inducible Cre recombination in Gfral-expressing cells/tissues (including neurons of the area postrema and nucleus of the solitary tract) and may be useful for studying feeding behavior, obesity, and metabolism.

型号：GM-J#036750 -Cryorecovery

应用：GfralCre mice have the endogenous GDNF family receptor alpha like (Gfral) promoter/enhancer sequences directing expression of Cre recombinase. These mice are a Cre-lox tool allowing Cre recombination in Gfral-expressing cells/tissues (including neurons of the area postrema and nucleus of the solitary tract) and may be useful for studying feeding behavior, obesity, and metabolism.

型号：GM-J#036749 -Cryorecovery

应用：Cckbrcre knock-in mice have the endogenous cholecystokinin B receptor promoter/enhancer sequences directing expression of Cre recombinase. These mice are a Cre-lox tool allowing Cre recombination in Cckbr-expressing cells/tissues (including neurons of the ventromedial nucleus of the hypothalamus), and may be useful in studying feeding behavior, obesity and diabetes.

型号：GM-J#036747 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#036704 -Cryorecovery

应用：Hic1CreERT2 mice have an IRES fused to a cre/ERT2 sequence inserted into the 3’ UTR of the Hic1 gene. This strain is useful for studying quiescent mesenchymal progenitor subpopulations and their role in tissue regeneration.

型号：GM-J#036703 -Cryorecovery

应用：Hic1f/f floxed mice have loxP sites flanking exon 2 of the Hic1 gene, which contains the translation initiation codon. These mice also contain a nuclear localized lacZ sequence downstream of the floxed region. This strain is useful for studying quiescent mesenchymal progenitor subpopulations and their role in tissue regeneration.