型号：GM-J#037333 -Cryorecovery

应用：Chodl-P2A-Cre knock-in mice are designed to have Cre recombinase expression/activity directed by the endogenous chondrolectin promoter/enhancer sequences. These mice may be used to generate conditional mutations for studying function of Chodl-expressing cells.

型号：GM-J#037318 -Available

应用：H3.1-iCOUNT (inducible cell division counter) knock-in mice carry a loxP-flanked mCherry reporter followed by an EGFP reporter inserted upstream of the H3c6 (H3 clustered histone 6, also called H3.1) stop codon. Mice may be used to label cell division events in vivo.

型号：GM-J#037286 -Cryorecovery

应用：Mgl2-cre knock-in mice contain a Cre recombinase inserted into the 3' UTR of the Mgl2 (macrophage galactose N-acetyl-galactosamine specific lectin 2) locus. Cre recombinase activity is observed specifically in type 2 conventional dendritic cell subsets. This strain may be useful in studies of CD4 T cell priming in the lymph node.

型号：GM-J#037269 -Available

应用：K8-creERT2 transgenic mice express a tamoxifen-inducible Cre recombinase (Cre-ERT2) and a GFP under the control of the Krt8 (keratin 8) promoter. Expression of cre/ERT2 recapitulates Krt8 expression. When bred with mice containing a loxP-flanked sequence, tamoxifen-inducible, cre-mediated recombination will result in deletion of the flanked sequences in Krt8 expressing cells. These mice may be useful in studies of simple epithelial cells, tissue lineage tracing, and in epithelial cancers.

型号：GM-J#037206 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#037205 -Cryorecovery

应用：BAC-hOPTNE50K transgenic mice overexpress low, near-physiological levels of human OPTN carrying the glaucoma-associated, autosomal dominant E50K (GAG to AAG) missense mutation fused to IRES-EGFP. Hemizygotes demonstrate age-related loss of retinal ganglion cells (RGCs) and selective visual impairment in contrast sensitivity by 18 months of age.

型号：GM-J#037156-JAX -Cryorecovery

应用：Cre recombinase expression is seen in dopamine D1 receptor-expressing neurons.

型号：GM-J#037122 -Available

应用：The cre recombinase/green fluorescent protein fusion protein, driven by the Nr4a1 (Nur77) promoter in these mice, is expressed mainly in a subset of myeloid lineage cells of the spleen. These mice may be useful in studying thymocyte positive- and negative-selection as well as lymphocyte activation.

型号：GM-J#037103 -Cryorecovery

应用：Atoh13*HA-P2A-Cre knock-in mice carry a CRISPR/Cas9 generated insertion of three HA tags and Cre recombinase just upstream of the stop codon of the Atoh1 gene. These mice are useful for lineage tracing, cell sorting, and gene manipulation of multiple cell types including cochlear hair cells (HCs).

型号：GM-J#037095 -Cryorecovery

应用：TPO-cre transgenic mice express Cre recombinase under the control of the human TPO promoter. They may be useful when studying thyrocytes and the generation of thyroid hormones.