型号：GM-J#036689 -Available For Pre-Order

应用：MLR39 (CPV2/Cre) mice express Cre recombinase in the lens fiber cells of the eye starting at approximately embryonic day 12.5 (E12.5). Cre recombinase is also expressed in some retinal pigment epithelial (RPE) cells. A tyrosinase minigene leads to very faint pigmentation in the coat and retinal pigment epithelium of homozygotes.

型号：GM-J#036687 -Cryorecovery

应用：iPKR knock-in/knock-out mice were developed for cell type-specific drug-inducible protein synthesis inhibition (ciPSI). They are a spatiotemporally precise chemogenetic tool for rapidly and reversibly blocking cell-autonomous protein synthesis via phosphorylation of eIF2α (EIF2A). Expression of Eef1a1 is knocked out by the targeted insertion and homozygotes are not viable.

型号：GM-J#036670 -Available

应用：The double mutant Stock No. 036670 was created by breeding PolgAD257Aneo males from Stock No. 017341 (B6.129S7(Cg)-Polgtm1Prol/J) to Parkin knock-out females from Stock No. 006582 (B6.129S4-Prkntm1Shn/J).

型号：GM-J#036668 -Cryorecovery

应用：These Grpricre knock-in mice have an IRES-icre recombinase gene inserted immediately downstream of the stop codon in the 3' UTR of the X-linked gastrin releasing peptide receptor (Grpr) gene. This strain may useful for inducing efficient icre recombinase activity in neurons of the spinal cord dorsal horn.

型号：GM-J#036591 -Available

应用：Fcrls-2A-Cre knock-in mice have the endogenous Fcrl2 (formerly Fcrls) promoter/enhancer sequences directing expression of Cre recombinase. These mice are a Cre-lox tool allowing Cre recombination in Fcrl2-expressing cells/tissues (primarily microglia), and may be useful in studying neural development and neurodegenerative diseases.

型号：GM-J#036577 -Cryorecovery

应用：The Ptf1aCre-ERTM knock-in allele was designed to both abolish pancreas specific transcription factor, 1a (Ptf1a) gene function and express CreERTM fusion protein from the Ptf1a promoter/enhancer elements. PTF1A effects growth and lineage specification of pancreatic multipotent progenitor cells during development.

型号：GM-J#036564 -Available

应用：Nav1.8-Cre knock-in/knock-out mice carry Cre recombinase under the control of the Scn10a (sodium channel, voltage-gated, type X, alpha or Nav1.8) promoter. Cre expression is observed beginning at E14 in small diameter neurons in dorsal root, trigeminal and nodose ganglia. Mice heterozygous for the mutation can be used as a tool in pain behavior studies to delete floxed genes only in nociceptors.

型号：GM-J#036551 -Cryorecovery

应用：MCH-Cre transgenic BAC mice express cre recombinase from the mouse Pmch (pro-melanin-concentrating hormone; also called MCH) promoter/enhancer regions. These mice, backcrossed to C57BL/6J and lacking the Pde6brd1 retinal degeneration allele, are useful in studies of MCH-neuronal activity in controlling energy balance, glucose homeostasis, sleep, locomotion, and reward-related behaviors.

型号：GM-J#036543 -Available

应用：Tpbpar/Adaf-AdaP-Cre transgenic mice express a cre recombinase directed by a mouse basal Ada (adenosine deaminase) promoter and a chimeric Tpbpar/Ada placental enhancer. Nuclear localized cre recombinase activity is observed in the placenta.

型号：GM-J#036525 -Cryorecovery

应用：These CCSPicre knock-in/knock-out mice contain an icre recombinase gene inserted upstream of the Scgb1a1 gene. This strain may useful for inducing efficient icre recombinase activity only in bronchiolar non-ciliated Clara cells.