产品型号:GM-J#037205 -Cryorecovery
产品应用:BAC-hOPTNE50K transgenic mice overexpress low, near-physiological levels of human OPTN carrying the glaucoma-associated, autosomal dominant E50K (GAG to AAG) missense mutation fused to IRES-EGFP. Hemizygotes demonstrate age-related loss of retinal ganglion cells (RGCs) and selective visual impairment in contrast sensitivity by 18 months of age.