型号:GM-J#037677 -Available
应用:LoxCode knock-in mice have the LoxCode cassette inserted into the endogenous Gt(ROSA)26Sor locus. The LoxCode cassette is composed of 14 loxP sites in alternating orientation flanking 13 small (8-14nts) code elements. Upon Cre exposure, random recombination between the loxP sites lead to inversions and excisions, resulting in DNA sequence reshuffling with a theoretical DNA diversity of over 30 billion barcodes. This is an inducible, cellular barcoding technology based on the Cre-loxP system that allows for sensitive, high diversity lineage tracing at the cellular, spatial, and tissue level.
型号:GM-J#037658 -Available
应用:Myh11-CreERT2-RAD transgenic mice allow sufficient Myh11-driven tamoxifen-inducible cre expression in smooth muscle cells (SMCs) in the brachiocephalic artery (BCA) and aorta. This transgene integrated into mouse Chromosome 2 in a region devoid of other genes [Chr2:178,826,578-178,826,802 (GRCm39)].
型号:GM-J#037643-JAX -Cryorecovery
应用:These microRNA cluster 10 (or Mir15b/Mir16-2) conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.
型号:GM-J#037633-JAX -Available
应用:Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.
型号:GM-J#037603 -Available
应用:Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.
型号:GM-J#037591 -Cryorecovery
应用:Dct::CreERT2 mice express cre/ERT2 fusion gene from the dopachrome tautomerase (Dct) promoter. These mice may be useful for studying melanocyte stem cells (McSCs) and differentiation of melanocyte lineage cells.
型号:GM-J#037580-JAX -Cryorecovery
应用:These CRE3 transgenic mice express Cre recombinase under the control of the rat myosin light chain II ventricular (Mylpf or MLC2v) promoter beginning at E11.5 in the brain. This strain may be useful for generating conditional deletions in neurons and their progenitors.
型号:GM-J#037578 -Cryorecovery
应用:Oxtr1xPA-iCre knock-in mice express a PA-tag and a codon improved cre recombinase (icre) under direction of the endogenous oxytocin receptor (Oxtr) promoter in brain regions. This mouse strain could be useful for manipulation of oxytocin receptor-expressing cells.
型号:GM-J#037551 -Cryorecovery
应用:This tamoxifen-inducible pdx1PB CreERTM strain on the diabetes susceptible NOD background may be used to create inducible pancreatic cell knockouts when crossed with strains carrying floxed alleles.
型号:GM-J#037540 -Cryorecovery
应用:Ins2-Cre knock-in mice express Cre recombinase under the direction of the Ins2 promoter in β cells of the pancreas.