型号：GM-J#008712 -Cryorecovery

应用：These Twist2-cre (or, Dermo1-cre) mutant mice harbor a Cre recombinase knock-in allele that also abolishes endogenous twist homolog 2 (Drosophila) (Twist2) gene function. They may be useful for Cre-lox applications/Twist2-deficiency research in embryogenesis of mesoderm-derived tissues (including chondrocytes and osteoblasts), as well as NF-kappaB transcription factor/cytokine signaling pathways.

型号：GM-J#008705 -Cryorecovery

应用：These IRG transgenic mice are a double-fluorescent, Cre-reporter strain; with widespread expression of red fluorescence prior to Cre recombinase exposure, and green fluorescence following cre-mediated recombination in a pattern determined by cre expression, and should provide a versatile tool for analyzing complex cellular relationships in a wide variety of tissues.

型号：GM-J#008694 -Cryorecovery

应用：Enhanced green fluorescent protein is expressed in FoxP3+ T cells. These Foxp3-GFP/cre mice may be useful in studies of regulatory T cell function in autoimmunity.

型号：GM-J#008678 -Cryorecovery

应用：These mice have a GFP-puror fusion protein "knock-in" mutation of the Ubb (ubiquitin B) gene that also abolishes endogenous gene function and may be useful for fluorescent labeling and/or Ubb-deficiency in studying gametogenesis, meiosis, neuron development and survival, neuropathogenic disease, and adult-onset obesity linked to selective hypothalamic neurodegeneration.

型号：GM-J#008661 -Available

应用：These Nkx2.1Cre (or BAC-Nkx2.1-Cre) transgenic mice express cre under the control of the Nkx2.1 promoter/enhancer regions and may be useful for generating conditional mutations for studying gain/loss of function or fate mapping in subgroups of brain progenitor cells (interneurons in telencephalon and hypothalamus cells), as well as developing lung, thyroid, and pituitary tissues.

型号：GM-J#008610 -Available

应用：Vav-iCre transgenic mice have the mouse HS21/45 control regions directing expression of an optimized variant of Cre recombinase (iCre) to hematopoietic cells (and their progenitors), and may be useful for generating conditional mutations in hematopoietic cells.

型号：GM-J#008606 -Cryorecovery

应用：Homozygous ROSA26 GNZ knock-in mice have widespread expression of a nuclear-localized green fluorescent protein/beta-galactosidase fusion protein (GFP-NLS-lacZ or GNZ) once an upstream loxP-flanked STOP sequence is removed. When bred to cre expressing mice, the resulting GNZ fusion protein expression in the offspring allows for enhanced (single cell level) visualization.

型号：GM-J#008605 -Cryorecovery

应用：These IRG transgenic mice are a double-fluorescent, Cre-reporter strain; with widespread expression of red fluorescence prior to Cre recombinase exposure, and green fluorescence following cre-mediated recombination in a pattern determined by cre expression, and should provide a versatile tool for analyzing complex cellular relationships in a wide variety of tissues.

型号：GM-J#008601 -Available

应用：TH-Cre transgenic mice have the rat tyrosine hydroxylase (TH) promoter directing expression of Cre recombinase to catecholaminergic cells, and may be useful for generating conditional mutations in these cells for studying dopaminergic cell function, Parkinson's disease, and other neurodegenerative disorders.

型号：GM-J#008569 -Cryorecovery

应用：This strain expresses Cre recombinase from the targeted Alpl (alkaline phosphatase, liver/bone/kidney) locus. These mice may be useful for generating tissue-specific deletions, primarily in embryonic primordial germ cells, for applications related to reproductive and endocrine systems development.