型号：GM-J#010529 -Cryorecovery

应用：In this strain, the mouse myogenic factor 5 (Myf5) promoter drives expression of both the targeted gene and cre in myoblast progenitors of skeletal muscle lineage and some cartilage progenitors in the ribs. Crossing this mouse with another carrying a loxP-flanked genomic segment of interest enables tissue-specific excision of the floxed segment in the offspring.

型号：GM-J#010528 -Cryorecovery

应用：In this strain, the mouse myogenic factor 6 (Myf6) promoter drives expression of both the targeted gene and cre in differentiated myocytes of skeletal muscle lineage. When crossed with a strain carrying a loxP-flanked genomic segment of interest, tissue-specific excision of that segment may be achieved in the offspring.

型号：GM-J#010523 -Cryorecovery

应用：These mice contain (STOP-hPLAP): the human alkaline phosphatase, placental (Regan isozyme), ALPP, gene under the control of the CAG (chicken beta actin promoter/enhancer and cytomegalovirus immediate-early enhancer) promoter, inserted into the Gt(ROSA)26Sor locus. Expression of the ALPP gene is blocked by a loxP-flanked STOP fragment placed between the ALPP sequence and the Gt(ROSA)26Sor promoter. This strain serves as a reporter strain, with successful Cre-mediated excision being indicated by ALPP expression in cre-expressing tissues.

型号：GM-J#009688 -Cryorecovery

应用：Dopamine-deficient (DA-deficient, DA-/-, or DD) mice are homozygous for the TH mutant allele and heterozygous for the DBH-TH mutant allele (Th-/-;DbhTh/+). While no expression from the TH mutant allele is observed in any tissues (resulting in deficiency of both dopamine (DA) and norepinephrine (NE)), the DBH-TH mutant allele contains the TH coding sequence under the control of the endogenous DBH promoter region and restores TH expression in noradrenergic neurons. These DD mice may be useful in studying dopaminergic neurobiology (including neurotransmitters, addiction, feeding, learning and memory, catecholamines, and Parkinsonian phenotypes).

型号：GM-J#009666 -Cryorecovery

应用：These Ppargc1a (peroxisome proliferative activated receptor, gamma, coactivator 1 alpha) conditional (floxed) mutant mice may be useful in generating conditional mutations for studying hepatic heme biosynthesis and porphyrias as well as neuromuscular junction physiology and muscular dystrophy.

型号：GM-J#009643 -Cryorecovery

应用：These transgenic mice express Cre recombinase under the control of the bovine LHB, luteinizing hormone beta polypeptide promoter. Cre recombinase expression is seen in mature pituitary gonadotropes, specifically in cells that produce luteinizing hormone beta. This strain represents an effective tool for generating tissue specific-targeted mutants that would be useful in the study of developmentally critical gene function in the pituitary.

型号：GM-J#009642 -Cryorecovery

应用：Cre recombinase expression is seen during development and in the adult in pituitary somatotropes. Weaker expression is detected in lactotropes. Cre expression is detected in the forelimb skin of embryos aged embryonic day 16.5-17.5 with weaker expression in adult kidney, ovary, and testis. This strain represents an effective tool for generating tissue specific-targeted mutants that would be useful for studying developmentally critical gene function in the anterior pituitary.

型号：GM-J#009616 -Cryorecovery

应用：These A930038C07Rik-Tg4-Cre mice express Cre recombinase under the control of the A930038C07Rik (RIKEN cDNA A930038C07 gene [also called epidermacan]) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex, striatum, and cerebellum).

型号：GM-J#009615 -Cryorecovery

应用：These Cart-Tg1-Cre mice express Cre recombinase under the control of the Cartpt (CART prepropeptide) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex, hippocampus, and cerebellum).

型号：GM-J#009614 -Cryorecovery

应用：These Wfs1-Tg2-CreERT2 mice express a tamoxifen-inducible Cre recombinase under the control of the mouse Wfs1 (Wolfram syndrome 1 homolog (human)) promoter/enhancer regions, and may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues (including cortex, hippocampus, and cerebellum).