型号:GM-J#017494 -Cryorecovery
应用:These Tshz3-GC transgenic mice express eGFPCre, Enhanced Green Fluorescent Protein and Cre recombinase, fusion gene under the direction of the mouse Tshz3 promoter and may be useful in studies of genitourinary system development.
型号:GM-J#017492 -Available
应用:The R26R-Confetti conditional allele has a CAG promoter followed by a floxed-STOP cassette and the Brainbow 2.1 construct all targeted into the Gt(ROSA)26Sor locus. The R26R-Confetti allele functions as a stochastic multicolor Cre recombinase reporter of multiple fluorescent proteins from a single genomic locus. These R26R-Confetti mice allow a way to label and distinguish individual / adjacent cells with nuclear localized, membrane-targeted, or cytoplasmic fluorescent proteins in cre recombined cells.
型号:GM-J#017491 -Available
应用:These Tagln-cre (also called Sm22aCre) transgenic mice express Cre recombinase under the control of the mouse smooth muscle protein 22-alpha (or transgelin) promoter. This strain represents an effective tool for generating tissue specific-targeted mutants that would be useful in studies of vascular diseases such as atherosclerosis.
型号:GM-J#017490 -Cryorecovery
应用:These Stra8-cre transgenic mice have expression of Cre recombinase (iCre) directed by the Stra8 genomic promoter fragment, and may be useful in generating conditional knockouts in postnatal, premeiotic, male germ cells for studying spermatogenesis.
型号:GM-J#017457 -Cryorecovery
应用:These transgenic mice carry both an mCherry fluorescent gene flanked by loxP sites and the yeast transcription activator protein GAL4 under the control of a cytomegalovirus enhancer/beta actin promoter (CAG). This strain may be effectively used as a component of the GAL4-UAS (Upstream Activation Sequence) system to activate gene transcription.
型号:GM-J#017456 -Cryorecovery
应用:These transgenic mice carry both an mCherry fluorescent gene flanked by loxP sites and the yeast transcription activator protein GAL4 under the control of a cytomegalovirus enhancer/beta actin promoter (CAG). This strain may be effectively used as a component of the GAL4-UAS (Upstream Activation Sequence) system to activate gene transcription.
型号:GM-J#017455 -Cryorecovery
应用:The R26-CAG-LSL-2XChETA-tdTomato reporter allele is designed to express two individual proteins following exposure to Cre recombinase; the ChR2-E123T accelerated (ChETA)/H134R variant of channelrhodopsin-2 and tdTomato fluorescent protein gene. When used with neuron-specific Cre recombinase expressing strains, the double mutant mice can be used in optogenetic studies and visualization of whole neurons.
型号:GM-J#017353 -Cryorecovery
应用:Expression of the YFP-Cre fusion gene in these mice is observed in Il13-expressing cells, including innate type 2 helper cells. These YetCre-13 mice may be useful for fluorescent reporter and/or Cre-lox studies of IL-13-expressing cells in type 2 immunity/host response to allergens and parasitic helminths.
型号:GM-J#017346 -Cryorecovery
应用:These A930038C07Rik-Tg1-Cre mice express Cre recombinase under the control of the A930038C07Rik (RIKEN cDNA A930038C07 gene [also called epidermacan]) promoter/enhancer regions within the BAC transgene. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in subgroups of brain tissues; specifically in neocortical deep layer 5 (Layer 5B) cells/thick-tufted pyramidal neurons of adult mice.
型号:GM-J#017336 -Available
应用:CD4-Cre transgenic mice contain CD4 enhancer, promoter and silencer sequences driving the expression of a Cre recombinase gene. These mice may be useful for generating conditional mutations in CD4-expressing tissues.