型号：GM-J#017682 -Available

应用：This transgenic line expresses human SNCA under the direction of a mouse Thy-1 promoter. Applications exist in studies related to Parkinson's disease and neurodegeneration elicited by the aggregation of SNCA.

型号：GM-J#017678 -Cryorecovery

应用：This double mutant strain expresses mutant human A53T alpha-synuclein (SNCA) and carries a targeted mutation for Pink1, PTEN induced putative kinase 1, and has applications in studies of the early stages of Parkinson's Disease.

型号：GM-J#017643 -Cryorecovery

应用：These 14qC3-CDRfl mice carry a floxed segment that encompasses sequence corresponding to a common deleted region (CDR) involved in most common B cell chronic lymphocytic leukemias in humans. They have applications in studies related to tumorigenesis and therapeutic management of chronic lymphocytic leukemia.

型号：GM-J#017642 -Cryorecovery

应用：These 14qC3-MDR mice carry a floxed region that encompases a region corresponding to a minimal deleted region involved in most common B cell chronic lymphocytic leukemias in humans. They have applications in studies related to tumorigenesis and therapeutic management of chronic lymphocytic leukemia.

型号：GM-J#017626 -Cryorecovery

应用：R26-LSL-tAGO2 mice are used in the miRAP (miRNA tagging and Affinity Purification) method in conjunction with Cre recombinase expressing mice, for genetically targeted microRNA tagging and generating tissue specific miRNA expression profiles.

型号：GM-J#017611 -Cryorecovery

应用：These Mcm2IRES-CreERT2 mice have Cre-ERT2 knocked into the minichromosome maintenance deficient 2 mitotin gene (Mcm2). Expression of Mcm2 is reduced, but not abolished. This strain may be useful for mediating inducible cre recombination in Mcm2-expressing tissues, as well as for studying the regulation of core DNA replication machinery.

型号：GM-J#017606 -Cryorecovery

应用：These HopxERCre knock-in mice harbor a tamoxifen-inducible CreERT2 fusion gene in the 3' UTR of the Hopx gene. Cre activity is observed in intestinal epithelial stem cells.

型号：GM-J#017595 -Cryorecovery

应用：These CAGGCre-ERTM transgenic mice have widespread expression of a tamoxifen-inducible Cre recombinase.

型号：GM-J#017593 -Available

应用：Sox2-CreER knock-in/knock-out mice have the Sox2 open reading frame replaced with a CreERT2 fusion gene. These mice may be useful for inducible Cre recombinase expression/floxed gene deletion in blastocysts, neural progenitor cells and in many adult epithelial tissues.

型号：GM-J#017585 -Cryorecovery

应用：These RERT mutant mice express the inducible Cre-ERT2 from the endogenous Polr2a locus.