型号:GM-J#025614 -Available
应用:These mice express tamoxifen-inducible cre recombinase (cre/ERT2) under the regulatory control of the mouse Th (tyrosine hydroxylase) gene.
型号:GM-J#025567 -Available
应用:Oligo2-cre mice express Cre recombinase under the direction of the Olig2 promoter in all oligodendrocyte-lineage cells and motor neurons.
型号:GM-J#025543 -Cryorecovery
应用:DscamfloxGOF is a dual fluorescent Cre reporter and conditional Dscam gain-of-function model; expressing red fluorescence in widespread cells/tissues prior to Cre recombinase exposure, with Down syndrome cell adhesion molecule overexpression and green fluorescence in Cre recombinase expressing cells. These mice may be useful for studying developmental neurobiology, central nervous system patterning and retinal organization. In addition, these mice allow one to test the similarities between Down syndrome and the reduced neuronal cell numbers and novel circuitry/neurite targeting defects associated with Dscam overexpression/mis-expression.
型号:GM-J#025533 -Cryorecovery
应用:These double mutant mice carry a targeted mutation for the Snca (synuclein, alpha) gene and a transgene consisting of the human SNCA under the direction of a mouse Thy-1 promoter. Applications exist in studies related to Parkinson's disease and neurodegeneration elicited by the aggregation of SNCA.
型号:GM-J#025524 -Available
应用:Cx3cr1-Cre mice express Cre recombinase under the direction of the Cx3cr1 promoter in the mononuclear phagocyte system making them useful for fate-mapping studies of the monocyte and macrophage compartment, as well as microglia. These mice do not express endogenous Cx3cr1.
型号:GM-J#025523 -Cryorecovery
应用:These mice express a codon improved Cre-recombinase in conventional dendritic cell precursors and may be useful for dendritic cell lineage fate mapping.
型号:GM-J#025521 -Cryorecovery
应用:Rax-CreERT2 mice express tamoxifen-inducible Cre recombinase under the direction of the Rax promoter. They are suitable for fate-mapping analysis in the developing and mature retina, hypothalamus and pituitary.
型号:GM-J#025520 -Cryorecovery
应用:These mice express Cre-ERT2 under the direction of the T promoter amaking them useful for applications requiring tamoxifen-induced deletion of floxed sequences during axis extension and somitogenesis.
型号:GM-J#025330 -Cryorecovery
应用:A copy number variation on human chromosome 16p11.2 is among the most common genetic variations found in autism spectrum disorders. 16p11flx mice are a Cre or FLP recombinase-inducible mouse model of 16p11.2 deletion that has several loxP and frt sites flanking the corresponding 440 kbp region on mouse chromosome 7F3. These mice may be useful in studying basal ganglia circuitry and the pathophysiology of autism.
型号:GM-J#025209 -Cryorecovery
应用:The Spp2G2aCE knock-in/knock-out allele was designed to both abolish Spp2 gene expression and express EGFP and Cre-ERT2 proteins from the Spp2 promoter in proximal tubule cells of the mouse kidney.