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  • STOCK Tg(CAG-RFP*,-Dscam,-EGFP)

    产品型号:GM-J#025543 -Cryorecovery

    产品应用:DscamfloxGOF is a dual fluorescent Cre reporter and conditional Dscam gain-of-function model; expressing red fluorescence in widespread cells/tissues prior to Cre recombinase exposure, with Down syndrome cell adhesion molecule overexpression and green fluorescence in Cre recombinase expressing cells. These mice may be useful for studying developmental neurobiology, central nervous system patterning and retinal organization. In addition, these mice allow one to test the similarities between Down syndrome and the reduced neuronal cell numbers and novel circuitry/neurite targeting defects associated with Dscam overexpression/mis-expression.

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