型号:GM-J#024864 -Cryorecovery
应用:These MIC transgenic mice express activated PyVT (Polyomavirus middle T antigen) and Cre recombinase under the control of a tetracycline-responsive promoter element (TRE or tetO) and are an effective tool for generating inducible, tissue-specific, targeted mutants to study polyomavirus middle T antigen (PyV mT)-mediated mammary tumorigenesis.
型号:GM-J#024849 -Cryorecovery
应用:The Thy1.2-Cre enhancer trap transgenic mouse line 09 (TFC.09) expresses Cre recombinase sparsely in a small number of cortical progenitor cells during early forebrain development. GFP expression is almost undetectable by fluorescence and it is only transiently expressed in a few stem cells in the embryo. TFC.09 mice allow examination of individual columns and cells, and may be useful for investigating patterns of neural development in the neocortex, as well as for studying cell lineage in mouse brain.
型号:GM-J#024846 -Cryorecovery
应用:ReaChR protein (a red-shifted channelrhodopsin) was tagged with mCitrine fluorescent protein and placed under the conditional control of the Gt(ROSA)26Sor promoter. Excision of two stop cassettes (one flanked by loxP sites, another flanked by FRT sites) enables fluorescent expression. As an optogenetic tool, this strain is useful for the selective activation and mapping of neuron populations.
型号:GM-J#024842 -Cryorecovery
应用:These Vil1-cre mice express Cre recombinase in villus and crypt epithelial cells of the small and large intestines and may be useful in studies of intestinal organogenesis. In addition, Villin-cre transgenic mice from founder line 1000 are reported to be absent of Cre recombinase activity in gonads.
型号:GM-J#024768 -Cryorecovery
应用:This TgUICBAC transgenic strain carries a transgene with tamoxifen inducible Cre recombinase. These mice may have applications in studies requiring conditional gene manipulation in the urothelium.
型号:GM-J#024713 -Cryorecovery
应用:These mice express cre recombinase from the skeletal muscle-specific myosin, light polypeptide 1 promoter.
型号:GM-J#024709 -Available
应用:These MIP1-CreERT mice express a transgene with tamoxifen inducible Cre recombinase in pancreatic beta cells.
型号:GM-J#024701 -Cryorecovery
应用:These transgenic mice have a tamoxifen inducible Cre-mediated recombination system driven by the mouse Plp1, proteolipid protein (myelin) 1 promoter. When crossed with a strain containing a loxP site flanked sequence of interest, the offspring are useful for generating tamoxifen-induced, Cre-mediated targeted deletions. Tamoxifen administration allows for ablation of predetermined genes in oligodendrocytes and Schwann cells, and will also induce Cre recombination in developing embryos of treated mothers and in cultured cells derived from transgenic mice.
型号:GM-J#024671 -Cryorecovery
应用:These transgenic mice express a tamoxifen-inducible cre recombinase from a Adipoq promoter. They may be useful in generating adipocyte-specific targeted mutants in studies related to adipose tissue function and storage, obesity, and other metabolic diseases.
型号:GM-J#024670 -Available
应用:These Ucp1-cre mice express Cre recombinase in interscapular brown fat at room temperature, and in inguinal and epididymal white adipose tissue after cold exposure.