型号：GM-J#028865 -Available

应用：Ai95(RCL-GCaMP6f)-D (also called Ai95D) mice are a Cre-dependent, fluorescent, calcium-indicator tool strain. Ai95D has a floxed-STOP cassette preventing transcription of the GCaMP6 fast variant calcium indicator (GCaMP6f; a detector of single neuronal action potentials with fast response kinetics). After Cre exposure, bright EGFP fluorescence is observed following calcium binding (such as neuronal activation).

型号：GM-J#028864 -Cryorecovery

应用：Sst-IRES-Cre knock-in mice express Cre recombinase in somatostatin-expressing neurons. These mice may be useful in studying dendritic inhibitory interneurons such as Martinotti cells and Oriens-Lacunosum-Moleculare cells.

型号：GM-J#028863 -Available Now

应用：Vglut2-ires-Cre knock-in mice have Cre recombinase expression directed to excitatory glutamatergic neuron cell bodies, without disrupting endogenous vesicular glutamate transporter 2 expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic neurons.

型号：GM-J#028862 -Available Now

应用：Vgat-ires-Cre knock-in mice have Cre recombinase expression directed to inhibitory GABAergic neuron cell bodies, without disrupting endogenous vesicular inhibitory amino acid transporter expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to GABAergic neuronal function.

型号：GM-J#028861 -Available

应用：ChAT-IRES-Cre knock-in mice express Cre recombinase in cholinergic neurons, without disrupting endogenous Chat expression. These mice may be useful in neurobiological research of motor function, learning and memory, Alzheimer's disease, and Down syndrome, as well as obesity and diabetes research.

型号：GM-J#028840 -Cryorecovery

应用：IL-21-Cre mice express codon-optimized Cre recombinase in IL-21 producing CD4+ T cell populations and may be useful in generating reporter mice that allow for the characterization and tracing of the development of IL-21 expressing cells.

型号：GM-J#028808 -Available

应用：These BAC-aSyn120 mice express a conditional mutant human synuclein, alpha (non A4 component of amyloid precursor), SNCA, gene directed by the human SNCA promoter/enhancer regions on the BAC transgene that produces a C-terminal truncated protein. These mice may be useful for studying SNCA function and the pathogenesis of Parkinson's disease.

型号：GM-J#028806 -Available

应用：These BAC-aSyn mice conditionally express a wild-type human synuclein, alpha (non A4 component of amyloid precursor), SNCA, gene directed by the human SNCA promoter/enhancer regions on the BAC transgene. These mice may be useful for studying SNCA function and the pathogenesis of Parkinson's disease.

型号：GM-J#028801 -Cryorecovery

应用：These LRRK2 S910A S935A knock-in mice carry 2 point mutations in exon 21 of the Lrrk2 gene and are suitable for use in applications related to the study of Parkinson's disease.

型号：GM-J#028764 -Cryorecovery

应用：Rosa26-lsl-GCaMP3 mice express the fluorescent calcium indicator protein GCaMP3 after exposure to Cre recombinase. Following subsequent calcium binding (such as neuronal activation), bright EGFP fluorescence is observed.