型号：GM-J#032291 -Available

应用：When these LysM-Cre ERT2 knock-in/knock-out mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the loxP-flanked sequences in myeloid cells. They are suitable for use in applications related to tamoxifen-inducible Cre-lox studies of the myeloid cell lineage (monocytes, mature macrophages and granulocytes) and the innate immune response.

型号：GM-J#032290 -Available

应用：MITO-Tag mice conditionally express, in a Cre recombinase-dependent manner, a hemagglutinin (HA)-tagged EGFP (codon-optimized) that localizes to mitochondrial outer membranes. These features enable immunocapture of mitochondria from specific cell types without the need for cell sorting techniques.

型号：GM-J#032285 -Available For Pre-Order

应用：The SLC34a1GCE mice express an eGFPCreERT2 fusion protein (EGFP and creERT2 fusion protein) from the Slc34a1 promoter/enhancer elements. These mice may be useful for studying fully differentiated proximal tubule epithelial cells and their role in repair after injury.

型号：GM-J#032205 -Cryorecovery

应用：When these CAMPER, cAMP Encoded Reporter, mice are crossed with a Cre recombinase expressing strain, the floxed-STOP cassette is deleted and the Gt(ROSA)26Sor and CAG promoters drive expression of the TEpacVV cAMP sensor in the Cre-expressing cells. CAMPER mice allow selective cAMP concentration changes monitoring via FRET imaging in a tissue/cell-specific manner and may be useful in studies of G-protein-coupled receptors (GPCRs) responses.

型号：GM-J#032198 -Not Available At Jax

应用：This strain has been discontinued. Please search the JAXMice database for strains carrying the Pdpn promoter/gene.

型号：GM-J#032102 -Cryorecovery

应用：This Msx2-creERT2 mutant mouse strain, carrying a transgene with tamoxifen-inducible Cre recombinase under the control of the mouse Msx2 (msh homeobox 2) promoter and enhancers, may be useful for generating targeted mutants specific to the apical ectodermal ridge (AER) and its underlying mesenchyme of the developing limb, and in studies of bone development and BMP signaling.

型号：GM-J#032090-JAX -Cryorecovery

应用：These Park7 knockout mice exhibit non-progressive hypokinesia, progressive gait abnormalities, decreased grip strength, loss of body weight and may be useful in studies of Parkinson's disease.

型号：GM-J#032080 -Cryorecovery

应用：E8III-Cre transgenic mice have the E8III enhancer and promoter elements from CD8 antigen, alpha chain (Cd8a) gene driving expression of Cre recombinase. These mice may be useful for deletion of genes of interest in CD8a expressing thymocytes.

型号：GM-J#032068 -Cryorecovery

应用：Cre-mediated excision of a loxP-flanked stop cassette enables tissue-specific expression of the INDIA apoptosis reporter in these Rosa26LSL-INDIA mice. When aCasp3 (Casp3, caspase 3; a marker for apoptosis) cleaves a linker, the mNeonGreen and mRuby2 components of INDIA are separated, resulting in FRET loss and increased emission from mNeonGreen.

型号：GM-J#032052 -Cryorecovery

应用：KitMCM mice express MerCreMer (cre/Esr*) tamoxifen-inducible cre recombinase from the mouse Kit (KIT proto-oncogene receptor tyrosine kinase) promoter. These mice have been useful in tracing the lineage of Kit-expressing cardiac cells.