型号：GM-J#032923 -Cryorecovery

应用：c-kitIRES-Cre mice have the endogenous Kit locus directing expression of Cre recombinase to molecular layer interneurons and Purkinje cells of the cerebellum in adult animals. These mice are useful in studies of neuron function in the adult mouse cerebellum.

型号：GM-J#032922-JAX -Cryorecovery

应用：These Ple162-EGFPCre;mEMS954 mice have the Ple162-EGFPCre transgene targeted as a single copy "knockin" into the upstream region of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus on the X chromosome. As the promoter/regulatory regions of the human paired-like homeodomain 3 (PITX3) gene direct expression of an EGFPCre fusion protein to a discrete, non-dopaminergic cell population in the ventral midbrain that borders the fasciculus retroflexus and the dorsal edge of the main dopaminergic population of the ventral tegmental area (VTA), these Ple162-EGFPCre;mEMS954 mice may be useful in studying PITX3-expressing cells in the brain and diseases affecting the brain, including mesocorticolimbic dopamine system function in the drug and natural reward circuitry of the brain, cognition, motivation, drug addiction, and psychiatric disorders.

型号：GM-J#032921-JAX -Cryorecovery

应用：These Ple178-EGFPCre;mEMS756 mice have the Ple178-EGFPCre transgene targeted as a single copy "knockin" into the upstream region of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus on the X chromosome. As the promoter/regulatory regions of the human regulator of G-protein signaling 16 (RGS16) gene direct expression of an EGFPCre fusion protein to hippocampus, thalamus, forebrain, cortex, brainstem, cerebellum, and retina, these Ple178-EGFPCre;mEMS756 mice may be useful in studying RGS16-expressing cells in the brain and diseases affecting the brain.

型号：GM-J#032911 -Cryorecovery

应用：HRGP-cre mice express Cre recombinase under the control of the retinal cone receptor cell-specific, human OPN1LW, opsin 1, long wave sensitive gene promoter. They are suitable for Cre-lox studies of cone photoreceptors.

型号：GM-J#032909 -Cryorecovery

应用：LMOP-cre mice express Cre recombinase under the control of the retinal rod cell specific mouse gene promoter, rhodopsin (Rho). They are suitable for Cre-lox studies of rod photoreceptors.

型号：GM-J#032883-JAX -Cryorecovery

应用：These knockin mutant mice possess a floxed GATA4 cDNA with a transcriptional stop cassette followed by an alkaline phosphatase cDNA; cre-mediated excision activates AP expression. This mutant mouse strain may be useful in studies of cell lineage tracing in the developing and adult heart.

型号：GM-J#032873 -Cryorecovery

应用：Pthrp-creER mice express cre/ERT2 fusion gene from the parathyroid hormone-like peptide (Pthlh) promoter. These mice may be useful for lineage mapping skeletal stem cell lineages.

型号：GM-J#032863 -Cryorecovery

应用：Mds1-CreERT2 mice conditionally express tamoxifen-inducible Cre recombinase knocked into the first exon of Mds1, the upstream start of transcription for the mouse Mecom locus. Cre recombinase is expressed from the MDS1-EVI1 isoform in the long-term and short-term hematopoietic stem cells upon tamoxifen induction.

型号：GM-J#032860 -Cryorecovery

应用：Cγ1-CreERT2 knock-in mice have a cre/ERT2 fusion gene inserted into the 3’ UTR of the immunoglobulin heavy constant gamma 1 (G1m marker) (Ighg1) gene. These mice are useful when studying normal and malignant germinal center B cell development in vivo.

型号：GM-J#032799 -Cryorecovery

应用：3KL-3798 transgenic mice express human SNCA with the E35K, E46K, and E61K mutations under the direction of the Thy1.2 (Thy1, thymus cell antigen 1, theta) promoter and pSer129 positive inclusions. They are suitable for use in applications related to the study of Parkinson's disease.