型号：GM-J#037718 -Available

应用：TIGRE2-jGCaMP8m-IRES-tTA2-WPRE knock-in mice co-express the jGCaMP8m genetically encoded calcium indicator (GECI) and a tetracycline controlled transactivator (tTA2) in a Cre recombinase-dependent manner from the intergenic Igs7 (TIGRE) locus. An internal ribosome entry site (IRES) introduced upstream of tTA ameliorates previously reported tTA overexpression toxicity issues. jGCaMP8m is noted for its faster decay rate and offers a useful compromise between sensitivity and kinetics.

型号：GM-J#037702 -Cryorecovery

应用：FAC (FLPo-dependent Adipoq-Cre) knock-in mice express a FLPo-inducible Cre recombinase under the control of the Adipoq (adiponectin, C1Q and collagen domain containing) endogenous promoter. Following FLPo-mediated recombination cre is expressed in adipose tissue. This strain may be used in studies of bone marrow adipocytes and bone homeostasis.

型号：GM-J#037698 -Cryorecovery

应用：Cre-iPEEL mice enable widespread Cre recombinase-gated ​expression of hemagglutinin (HA)-tagged, plasma membrane-targeted, extracellularly-facing horseradish peroxidase (HRP), allowing for proximity labeling, biochemical capture, and proteomic profiling of cell-surface proteins ​in a cell-type-specific manner.

型号：GM-J#037697 -Cryorecovery

应用：Dual-iPEEL mice enable widespread Cre and Flp recombinase-gated ​expression of hemagglutinin (HA)-tagged, plasma membrane-targeted, extracellularly-facing horseradish peroxidase (HRP), allowing for proximity labeling, biochemical capture, and proteomic profiling of cell-surface proteins ​in a cell-type-specific manner.

型号：GM-J#037677 -Available

应用：LoxCode knock-in mice have the LoxCode cassette inserted into the endogenous Gt(ROSA)26Sor locus. The LoxCode cassette is composed of 14 loxP sites in alternating orientation flanking 13 small (8-14nts) code elements. Upon Cre exposure, random recombination between the loxP sites lead to inversions and excisions, resulting in DNA sequence reshuffling with a theoretical DNA diversity of over 30 billion barcodes. This is an inducible, cellular barcoding technology based on the Cre-loxP system that allows for sensitive, high diversity lineage tracing at the cellular, spatial, and tissue level.

型号：GM-J#037658 -Available

应用：Myh11-CreERT2-RAD transgenic mice allow sufficient Myh11-driven tamoxifen-inducible cre expression in smooth muscle cells (SMCs) in the brachiocephalic artery (BCA) and aorta. This transgene integrated into mouse Chromosome 2 in a region devoid of other genes [Chr2:178,826,578-178,826,802 (GRCm39)].

型号：GM-J#037643-JAX -Cryorecovery

应用：These microRNA cluster 10 (or Mir15b/Mir16-2) conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.

型号：GM-J#037633-JAX -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#037603 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#037591 -Cryorecovery

应用：Dct::CreERT2 mice express cre/ERT2 fusion gene from the dopachrome tautomerase (Dct) promoter. These mice may be useful for studying melanocyte stem cells (McSCs) and differentiation of melanocyte lineage cells.