型号：GM-J#004126 -Cryorecovery

应用：Homozygous mice are Cd19-deficient, whereas heterozygous mice are phenotypically normal and can be used for specific deletion of floxed targets in B-lymphocytes. Homozygous mice are severely impaired in their ability to respond to T-cell-dependent antigens and fail to form splenic germinal centers. A deficiency in the B-1 subset of B-lymphocytes is observed along with a concomitant reduction in serum IgM.

型号：GM-J#004077 -Available

应用：These mice contain an Enhanced Green Fluorescent Protein (EGFP) gene inserted into the Gt(ROSA)26Sor locus. This strain serves as a reporter strain, with successful Cre excision being indicated by EGFP expression in cre-expressing tissues. The expression level in this reporter strain is suitable for applications involving FACS but is too low for histological applications.

型号：GM-J#003967 -Cryorecovery

应用：These transgenic mice express Cre recombinase under the direction of a Rbp3 promoter. Homozygous mice are prone to eye defects and females may be infertile. Recombinase activity is detected in photoreceptor cells.

型号：GM-J#003966 -Available

应用：Specific cre expression in neuronal cells of these mice is controlled by the rat Synapsin I promoter. These mice may be useful when mated to floxed genes of interest in studies of neural development and disorders such as Neurofibromatosis type 1.

型号：GM-J#003960 -Cryorecovery

应用：These 98030B Prion.GFPCre mice express a transgene containing cre and green fluorescent protein with cre expression observed in the germline.

型号：GM-J#003920 -Cryorecovery

应用：Expression of lacZ in these mice is under the control of the CMV enhancer/chicken actin promoter and is widespread except in liver and lung tissue. When crossed with a Cre recombinase-expressing strain, lacZ expression is replaced with GFP in tissues expressing cre.

型号：GM-J#003919 -Cryorecovery

应用：These Z/AP reporter mice express a transgene containing a floxed Beta-geo and the human placental alkaline phosphatase gene with widespread expression of lacZ except in erythrocytes, chondrocytes and adipocytes.

型号：GM-J#003855 -Cryorecovery

应用：These NOD.RIP-cre, line5 transgenic mice express Cre recombinase and can be used in combination with a floxed target gene to create various pancreatic beta cell-specific gene knockouts.

型号：GM-J#003829 -Cryorecovery

应用：These Wnt-1/GAL4/cre-11 transgenic mice have expression of both Cre recombinase and the GAL4 transcriptional activator directed to midbrain and developing neural tube by the wingless-related MMTV integration site 1 (Wnt1) promoter/regulatory sequences. When Wnt-1/GAL4/cre-11 transgenic mice are bred to mice containing loxP site-flanked sequences, cre-mediated recombination results in deletion of the floxed sequences in the midbrain and developing neural tube of the resulting offspring.

型号：GM-J#003802 -Available

应用：This transgenic strain expresses Cre under the control of the Lck (lymphocyte protein tyrosine kinase) promoter, enabling thymocyte-specific excision of loxP-flanked sequences of interest. The Lck gene is primarily expressed by T lymphocytes and it plays a key role in the selection and maturation of developing T-cells in the thymus and in the activity of mature T-cells.