型号：GM-J#019696 -Cryorecovery

应用：CD11b-cre mice express cre recombinase from the human ITGAM (integrin alpha M; also called CD11b) promoter enabling excision of loxP-flanked sequences in macrophages and granulocytes of bone marrow and spleen, as well as some CD4+ T and B220+ B lymphocytes. Recombination in microglia is undetectable.

型号：GM-J#019509 -Cryorecovery

应用：OC-cre transgenic mice express cre-recombinase in osteoblasts and may be useful in applications related to the study of bone and skeletal development.

型号：GM-J#019380 -Cryorecovery

应用：The INV-CreERT2 allele expresses a CreERT2 fusion protein from the human involucrin Ivl promoter. They may have applications studies related to epidermal lineage tracing.

型号：GM-J#019378 -Cryorecovery

应用：The Ptf1aCre-ERTM knock-in allele was designed to both abolish pancreas specific transcription factor, 1a (Ptf1a) gene function and express CreERTM fusion protein from the Ptf1a promoter/enhancer elements. PTF1A effects growth and lineage specification of pancreatic multipotent progenitor cells during development.

型号：GM-J#019148 -Available

应用：Agc1tm(IRES-CreERT2) mice express tamoxifen-inducible CreERT2 from the aggrecan promoter. These mice may be useful for studying cartilage degenerative diseases such as osteoarthritis and degenerative disk disease.

型号：GM-J#019106 -Available

应用：These mice express the mutant D409V GBA1 protein and possess loxP sites flanking exons 6 through 8 of the Gba1 (glucosidase, beta, acid 1) gene. They have applications in studies related to Parkinson's disease, Gaucher disease and synucleinopathies.

型号：GM-J#019102 -Cryorecovery

应用：These CAGGCre-ERTM transgenic mice exhibit widespread expression of a tamoxifen-inducible Cre recombinase.

型号：GM-J#019099 -Available

应用：These β-actin-cre transgenic mice express Cre recombinase directed by the human beta actin gene promoter. Cre recombinase activity is widespread in the embryo by the blastocyst stage of development.

型号：GM-J#019098 -Cryorecovery

应用：These Tg(Csf1r-Mer-iCre-Mer)1Jwp transgenic mice express the tamoxifen-inducible MerCreMer fusion protein under control of the macrophage specific mouse Csf1r, colony stimulating factor 1 receptor, promoter.

型号：GM-J#019096 -Cryorecovery

应用：The LysMcre knock-in/knockout allele has a nuclear-localized Cre recombinase inserted into the first coding ATG of the lysozyme 2 gene (Lyz2); both abolishing endogenous Lyz2 gene function and placing NLS-Cre expression under the control of the endogenous Lyz2 promoter/enhancer elements. These LysMcre mice may be useful for Cre-lox studies of the myeloid cell lineage (monocytes, mature macrophages and granulocytes) and the innate immune response.