型号：GM-J#028547 -Cryorecovery

应用：These Cyp17iCre transgenic mice have the mouse Cyp17a1 promoter driving codon optimized iCre recombinase expression in the ovarian theca/interstitial cells and Leydig cells in the testis.

型号：GM-J#028538 -Available

应用：These zDC-Cre knock-in mice express cre recombinase from the Zbtb46 promoter, enabling excision of loxP-flanked sequences in classical dendritic cells (cDCs).

型号：GM-J#028536 -Cryorecovery

应用：Ndnf-IRES2-dgCre-D knock-in mice have Cre recombinase expression directed by endogenous neuron-derived neurotrophic factor promoter/enhancer elements, without disrupting endogenous Ndnf expression. Although designed to be trimethoprim-inducible, the Cre recombinase activity is specific and efficient with or without TMP. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping in subgroups of neuronal populations (cortical layer 1, olfactory areas, hippocampal formation, striatum, midbrain and vascular cells).

型号：GM-J#028535 -Cryorecovery

应用：Ctgf-2A-dgCre-D knockin mice express a trimethoprim-inducible EGFP/Cre fusion gene directed by endogenous connective tissue growth factor promoter/enhancer elements, without disrupting endogenous Ctgf expression. When induced, Cre recombinase activity is restricted to layer 6b of the cortex and in restricted populations within the cortical subplate (e.g., endopiriform nucleus). These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping in these subgroups of brain tissues.

型号：GM-J#028534 -Available

应用：Slc17a8-IRES2-Cre-D knockin mice have Cre recombinase expression directed to Vglut3-expressing cells, without disrupting endogenous vesicular glutamate transporter 3 expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic synaptic vesicle trafficking.

型号：GM-J#028533 -Cryorecovery

应用：Cart-IRES2-Cre-D knockin mice have Cre recombinase expression directed to CART prepropeptide-expressing cells, without disrupting endogenous Cartpt expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping in subgroups of brain tissues (including cortex, cerebral nuclei, hypothalamus and midbrain) in regards to feeding, appetite and stress response, as well as gene regulation by cocaine and other drugs.

型号：GM-J#028532 -Available

应用：Calb1-IRES2-Cre-D knockin mice are designed to have Cre recombinase expression directed to calbindin 1-expressing cells in the hippocampus, striatum, thalamus, midbrain and cerebellum, without disrupting endogenous Calb1 expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to this calcium-binding protein.

型号：GM-J#028387 -Cryorecovery

应用：Atp13a2 floxed mice have loxP sites flanking exons 2-3 of the Atp13a2 gene. These mice may be useful for studying endolysosomal dysfunction, α-synuclein accumulation, and neurodegeneration associated with the onset of Parkinson’s disease.

型号：GM-J#028365 -Cryorecovery

应用：These Ngn3-CreERT2 transgenic mice express a tamoxifen-inducible Cre recombinase directed to Neurog3-expressing cells. When induced, Cre recombinase activity is observed in endocrine progenitor cells, pancreatic islet cells and intestinal enteroendocrine cells.

型号：GM-J#028364 -Cryorecovery

应用：These NeuroD1-Cre mice have the mouse neurogenic differentiation 1 (Neurod1) promoter driving Cre recombinase expression in Neurod1 expressing endocrine precursor cells in the pancreas, stomach and intestine.