型号：GM-J#028862 -Available Now

应用：Vgat-ires-Cre knock-in mice have Cre recombinase expression directed to inhibitory GABAergic neuron cell bodies, without disrupting endogenous vesicular inhibitory amino acid transporter expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to GABAergic neuronal function.

型号：GM-J#028861 -Available

应用：ChAT-IRES-Cre knock-in mice express Cre recombinase in cholinergic neurons, without disrupting endogenous Chat expression. These mice may be useful in neurobiological research of motor function, learning and memory, Alzheimer's disease, and Down syndrome, as well as obesity and diabetes research.

型号：GM-J#028840 -Cryorecovery

应用：IL-21-Cre mice express codon-optimized Cre recombinase in IL-21 producing CD4+ T cell populations and may be useful in generating reporter mice that allow for the characterization and tracing of the development of IL-21 expressing cells.

型号：GM-J#028808 -Available

应用：These BAC-aSyn120 mice express a conditional mutant human synuclein, alpha (non A4 component of amyloid precursor), SNCA, gene directed by the human SNCA promoter/enhancer regions on the BAC transgene that produces a C-terminal truncated protein. These mice may be useful for studying SNCA function and the pathogenesis of Parkinson's disease.

型号：GM-J#028806 -Available

应用：These BAC-aSyn mice conditionally express a wild-type human synuclein, alpha (non A4 component of amyloid precursor), SNCA, gene directed by the human SNCA promoter/enhancer regions on the BAC transgene. These mice may be useful for studying SNCA function and the pathogenesis of Parkinson's disease.

型号：GM-J#028801 -Cryorecovery

应用：These LRRK2 S910A S935A knock-in mice carry 2 point mutations in exon 21 of the Lrrk2 gene and are suitable for use in applications related to the study of Parkinson's disease.

型号：GM-J#028764 -Cryorecovery

应用：Rosa26-lsl-GCaMP3 mice express the fluorescent calcium indicator protein GCaMP3 after exposure to Cre recombinase. Following subsequent calcium binding (such as neuronal activation), bright EGFP fluorescence is observed.

型号：GM-J#028732 -Cryorecovery

应用：Tcfcp2l1GCE knock-in mice express a EGFP/cre/ERT2 fusion protein in acinar and duct cells of the salivary gland, and in the lacrimal glands. These mice may have applications in studies requiring conditional gene manipulation in the salivary gland, as well as in acinar or duct cell lineage fate mapping.

型号：GM-J#028731 -Cryorecovery

应用：Dcpp1GCE knock-in mice express a EGFP/cre/ERT2 fusion protein in serous demilune cells of the sublingual gland and intercalated duct cells of the parotid gland. These mice may have applications in studies requiring conditional gene manipulation or cell lineage tracing in sublingual and parotid glands.

型号：GM-J#028720 -Cryorecovery

应用：These floxed mutant mice possess loxP sites flanking exons 1 and 2 of the Nfkb2 gene. This strain may be useful for generating conditional mutations in applications related to the study of the B-cell nuclear factor-ΚB (NF-ΚB) pathway. Cre-mediated recombination also results in expression of GFP (Green Fluorescent Protein) which can be used to trace Nfkb2 ablation.