型号：GM-J#028719 -Cryorecovery

应用：These floxed mutant mice possess loxP sites flanking exons 1 and 2 of the Relb gene. This strain may be useful for generating conditional mutations in applications related to the study of the B-cell nuclear factor-ΚB (NF-ΚB) pathway. Cre-mediated recombination also results in expression of GFP (Green Fluorescent Protein) which can be used to trace Relb ablation.

型号：GM-J#028717 -Cryorecovery

应用：These Esr2-iCre knock-in/knock-out mice express codon optimized Cre recombinase from the endogenous Esr2 locus. Cre recombinase expression mimics endogenous Esr2 gene expression.

型号：GM-J#028678 -Cryorecovery

应用：Floxopatch (also called Optopatch) mice are a sensitive, fast optogenetic tool for targeted, simultaneous optical perturbation and measurement of membrane voltage. Animals express variants of a near-infrared archaerhodopsin-based voltage indicator (QuasAr2-dark mOrange2; QuasAr2 is near infrared fluorescent, dark mOrange2 is non-fluorescent) and a blue light-gated channelrhodopsin actuator (CheRiff-EGFP; green fluorescent) in the cell plasma membrane after cre-mediated excision of a floxed Stop cassette.

型号：GM-J#028658 -Cryorecovery

应用：This Sox10ERT2CreERT2 (SECE17) strain, carrying a transgene with tamoxifen inducible Cre recombinase under the control of the Sox10 MCS4 enhancer/c-Fos minimal promoter, may be useful for generating spatiotemporal neural crest cell specific targeted mutants for studies of neural crest-derived cell populations during embryonic development.

型号：GM-J#028583 -Cryorecovery

应用：These RGBow reporter mice express one of three membrane-tethered fluorescent proteins in a random manner upon cre-mediated recombination; this allows labeling of individual cell types with distinguishable color variations in cre recombined cells.

型号：GM-J#028582 -Cryorecovery

应用：These IS reporter mice harbor a targeted mutation of the Gt(ROSA)26Sor locus with a loxP-flanked STOP cassette and a frt-flanked tdTomato sequence preventing transcription of a CAG promoter-driven enhanced green fluorescent protein (EGFP). tdTomato is expressed following Cre-mediated recombination. EGFP is only expressed following Cre-mediated and Flp-mediated recombination. This strain may be useful as an intersectional reporter for cre and FLP expression, or as a subtraction reporter for cre expression alone.

型号：GM-J#028581 -Cryorecovery

应用：These HG-dual mice harbor a targeted mutation of the Gt(ROSA)26Sor locus with a loxP-flanked STOP cassette and a frt-flanked STOP cassette preventing transcription of a CAG promoter-driven enhanced green fluorescent protein (EGFP). EGFP is only expressed following Cre-mediated and Flp-mediated recombination. This strain may be useful as an intersectional reporter for cre and FLP expression.

型号：GM-J#028580 -Cryorecovery

应用：PV-2A-CreER knock-in mice express the CreERT2 fusion protein in parvalbumin positive neurons of the neocortex and cerebellum, as directed by the endogenous Pvalb promoter/enhancer elements.

型号：GM-J#028560 -Cryorecovery

应用：These SncaΔflox Rosa26-stop-lacZ reporter mice carry a knock out allele of the Snca gene and the Gt(ROSA)26Sortm1Sho Cre reporter allele. This strain may be useful for generating mutants in which Cre recombinase efficiency can be monitored for applications related to neurodegenerative synucleinopathies, such as Parkinson's disease and multiple system atrophy.

型号：GM-J#028559 -Cryorecovery

应用：These "SncaΔflox" knock-out mice mutant mice lack the first coding exon (exon II) of the Snca (synuclein, alpha) gene. This strain may be useful in studies related to neurodegenerative synucleinopathies, such as Parkinson's disease and multiple system atrophy.