型号:GM-J#021024 -Cryorecovery
应用:Csf1r-iCre transgenic mice have codon optimized Cre recombinase (iCre) expression under direction of the murine colony stimulating factor 1 receptor promoter (Csf1r). iCre recombinase expression is evident in immune cells, including macrophages, dendritic cells and bone marrow derived granulocytes.
型号:GM-J#021012 -Cryorecovery
应用:These transgenic mice carry the Brainbow 1.0 cassette, incorporating dTomato, mCerulean, and EYFP, driven by the broadly-expressed CAG (CMV-chicken beta actin) promoter. These fluorescent markers are useful in tracing cell lineage.
型号:GM-J#021011 -Cryorecovery
应用:These transgenic mice carry the Brainbow 1.0 cassette, incorporating dTomato, mCerulean, and EYFP, driven by the broadly-expressed CAG (CMV-chicken beta actin) promoter. These fluorescent markers are useful in tracing cell lineage.
型号:GM-J#020940 -Available
应用:Cx3cr1CreER knock-in/knock-out mice express tamoxifen-inducible Cre recombinase under the direction of the Cx3cr1 promoter in the mononuclear phagocyte system making them useful for fate-mapping studies of the monocyte and macrophage compartment, as well as microglia.
型号:GM-J#020550 -Cryorecovery
应用:RGS9-cre knock-in mice express Cre recombinase under the direction of the endogenous Rgs9 promoter predominantly in the striatum.
型号:GM-J#020505 -Available
应用:These mb1-cre knock-in/knock-out mice carry an allele in which exons 2 and 3 of the Cd79a gene have been replaced with a codon optimized Cre recombinase gene and the ATG codon of exon 1 is deleted; both abolishing endogenous Cd79a gene function and placing cre expression under the control of the endogenous Cd79a promoter/enhancer elements. Cre recombinase expression is directed at the earliest stages and throughout B-lymphocyte development and differentiation. Homozygous mice are also useful for studying B cell-deficiency.
型号:GM-J#020458 -Cryorecovery
应用:In these R26StopFLMYC mice, Cre recombinase-mediated excision of a floxed STOP cassette allows expression of a CAG promoter driven human MYC (avian)) cDNA and truncated signaling deficient human CD2 (CD2 molecule) from the Gt(ROSA)26Sor locus. These mice may be useful in general studies of the role of MYC, including of its function in germinal center development, B cell proliferation and immune response.
型号:GM-J#020287 -Cryorecovery
应用:These mice express prostate specific tamoxifen-inducible cre, and may be useful when studying prostate specific disorders.
型号:GM-J#020282 -Available
应用:vil-Cre-ERT2 mice carry a transgene with tamoxifen inducible Cre recombinase under the control of the 9 kb mouse Vil1, villin 1, promoter, and may be useful for generating specific targeted mutants for studies of the crypt-villus axis of the intestinal epithelium.
型号:GM-J#020080 -Cryorecovery
应用:The DAT-cre "knock-in" allele has a nuclear-localized Cre recombinase inserted just upstream of the first coding ATG of the dopamine transporter gene (Slc6a3; DAT). This was designed to both abolish DAT gene function and place Cre recombinase expression under the control of the DAT promoter/enhancer elements.