产品型号：GM-J#020505 -Available

产品应用：These mb1-cre knock-in/knock-out mice carry an allele in which exons 2 and 3 of the Cd79a gene have been replaced with a codon optimized Cre recombinase gene and the ATG codon of exon 1 is deleted; both abolishing endogenous Cd79a gene function and placing cre expression under the control of the endogenous Cd79a promoter/enhancer elements. Cre recombinase expression is directed at the earliest stages and throughout B-lymphocyte development and differentiation. Homozygous mice are also useful for studying B cell-deficiency.