型号:GM-J#026862 -Cryorecovery
应用:ROSAmT/mG is a cell membrane-targeted, two-color fluorescent Cre reporter allele; expressing cell membrane-localized red fluorescence in widespread cells/tissues prior to Cre recombinase exposure, and cell membrane-localized green fluorescence in Cre recombinase expressing cells (and future cell lineages derived from these cells). These ROSAmT/mG mice function similarly to ROSAnT-nG mice (Stock No. 023035), with ROSAmT/mG directed to cell membrane and ROSAnT-nG directed to nuclei.
型号:GM-J#026861 -Cryorecovery
应用:The LysMcre knock-in/knockout allele has a nuclear-localized Cre recombinase inserted into the first coding ATG of the lysozyme 2 gene (Lyz2); both abolishing endogenous Lyz2 gene function and placing NLS-Cre expression under the control of the endogenous Lyz2 promoter/enhancer elements. These LysMcre mice may be useful for Cre-lox studies of the myeloid cell lineage (monocytes, mature macrophages and granulocytes) and the innate immune response.
型号:GM-J#026860 -Cryorecovery
应用:Mice harboring the Tg(Tek-cre)2352Rwng (Tie2Cre) transgene express the Cre recombinase under the control of the mouse Tek, endothelial-specific receptor tyrosine kinase (also known as Tie2), promoter and may be useful for generating endothelial cell specific-targeted conditional mutations.
型号:GM-J#026859 -Cryorecovery
应用:These Sox2Cre transgenic mice express Cre recombinase under the control of the mouse Sox2 (SRY-box containing gene 2) promoter, and may be useful for generating epiblast-derived specific conditional mutations.
型号:GM-J#026858 -Cryorecovery
应用:This knock-in strain expresses Cre recombinase under the control of the endogenous Meox2 promoter with Cre recombinase active in early embryos. These mice can be utilized as a deleter strain for floxed genes and provide an alternative to tetraploid embryo analysis.
型号:GM-J#026857 -Cryorecovery
应用:These transgenic mice express Cre recombinase under the control of the human glial fibrillary acidic protein promoter (GFAP). Recombination occurs primarily in the central nervous system, affecting astrocytes, oligodendroglia, ependyma and some neurons.
型号:GM-J#026855 -Cryorecovery
应用:These Brainbow 1.1 (founder line M) mice allow mutually exclusive expression of three membrane-targeted fluorescent proteins in astrocytes (including glia) throughout the brain, providing unambiguous delineation of boundaries between adjacent astrocytes in cre recombined cells, and may also be useful in conjunction with other Brainbow strains (Stock No's. 007901, 007910, and 007921) for neurobiological studies.
型号:GM-J#026854 -Cryorecovery
应用:These Brainbow transgenic mice allow labeling of individual neuronal types with approximately 166 distinguishable color variations in cre recombined cells, and may also be useful in conjunction with other Brainbow strains for neurobiological studies.
型号:GM-J#026852 -Cryorecovery
应用:GFAP-Cre transgenic mice from founder line 73.12 have Cre recombinase expression directed by the mouse glial fibrillary acidic protein promoter. Cre expression is observed in astrocytes in the brain and spinal cord, as well as postnatal and adult GFAP-expressing neural stem cells and their progeny in the brain.
型号:GM-J#026828 -Cryorecovery
应用:This Cpa3-Cre strain is useful in analyzing the roles of mast cells, basophils, some populations of T-cell progenitors, thymic T cells and hematopoietic progenitor cells.