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  • B6.Cg-Igs7tm140.1(tetO-EGFP,CAG-tTA2)

    产品型号:GM-J#030220 -Cryorecovery

    产品应用:Ai140(TIT2L-GFP-ICL-tTA2)-D (also called Ai140D) mice are a Cre-dependent, Tet-controllable fluorescent reporter line, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). Exposure to Cre recombinase removes both STOP cassettes - resulting in EGFP fluorescence and tTA2 expression - and that EGFP expression may be diminished/eliminated by doxycycline.

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