型号：GM-J#033089 -Cryorecovery

应用：Cre recombinase-mediated excision of a floxed neomycin cassette enables these R26-CAG-LNL-GtACR1-Fred-Kv2.1 mice to conditionally express GtACR1 (Guillardia theta anion channel rhodopsin 1) fused with Kv2.1 (Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1) soma trafficking domain and FusionRed fluorescent protein (Fred). This strain enables selective, conditional optogenetic hyperpolarization, silencing and labeling of neurons.

型号：GM-J#033055 -Cryorecovery

应用：VEC-cre transgenic mice express Cre recombinase under the control of a Cdh5 promoter with greater efficiency than other similar lines. They may have applications related to the study of hematopoietic stem cell lineages derived from vascular endothelial cells.

型号：GM-J#033052 -Cryorecovery

应用：ProcrCreERT2-IRES-tdTomato are knockin/knockout mice with an inducible cre/ERT2 fusion gene followed by a tdTomato reporter inserted into the ATG codon of the protein C receptor (Procr). These mice can be used to identify multipotent mammary stem cells (MaSCs) in the basal layer of the mammary epithelium.

型号：GM-J#033026 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#033019 -Cryorecovery

应用：Mice harboring the vil-Cre transgene have the 9-kb mouse, Vil1, villin 1, promoter directing expression of Cre recombinase to the intestinal epithelia and kidney, and may be useful for generating conditional mutations in cells of the crypt villus axis and kidney. This strain also is available on the C57BL/6J background (Stock No. 035595).

型号：GM-J#032998-JAX -Cryorecovery

应用：In this ROSA NOTCH3-WT76 knockin strain, expression of the human NOTCH3 is blocked by an upstream loxP-flanked STOP sequence. Cre-mediated excision results in expression of human NOTCH3 and GFP targeted to the nucleus. Expression of NOTCH3 in vascular smooth muscle cells rescues the stroke susceptibility phenotype of Notch3 knockout mice.

型号：GM-J#032928-JAX -Cryorecovery

应用：These mice have the Ple167-EGFP/NLS-cre transgene targeted as a single copy "knockin" into the upstream region of the Hprt1 locus on the X chromosome. The promoter/regulatory regions of the human POGZ gene directs expression of an enhanced green fluorescent protein/Cre recombinase fusion protein.

型号：GM-J#032926-JAX -Cryorecovery

应用：These mice have the Ple103-EGFP/cre transgene targeted as a single copy "knockin" into the upstream region of the Hprt1 locus on the X chromosome. The promoter/regulatory regions of the human HAP1 gene direct expression of an enhanced green fluorescent protein/Cre recombinase fusion protein.

型号：GM-J#032924-JAX -Cryorecovery

应用：These Ple177-EGFPCre;mEMS762 mice have the Ple177-EGFPCre transgene targeted as a single copy "knockin" into the upstream region of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus on the X chromosome. As the promoter/regulatory regions of the human regulator of G-protein signaling 16 (RGS16) gene direct expression of an EGFPCre fusion protein to hippocampus, thalamus, forebrain, cortex, brainstem, cerebellum, and retina, these Ple177-EGFPCre;mEMS762 mice may be useful in studying RGS16-expressing cells in the brain and diseases affecting the brain.

型号：GM-J#032923-JAX -Cryorecovery

应用：These Ple176-EGFPCre;mEMS759 mice have the Ple176-EGFPCre transgene targeted as a single copy "knockin" into the upstream region of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus on the X chromosome. As the promoter/regulatory regions of the human regulator of G-protein signaling 16 (RGS16) gene direct expression of an EGFPCre fusion protein to hippocampus, thalamus, forebrain, cortex, brainstem, cerebellum, and retina, these Ple176-EGFPCre;mEMS759 mice may be useful in studying RGS16-expressing cells in the brain and diseases affecting the brain.