产品型号:GM-J#032998-JAX -Cryorecovery
产品应用:In this ROSA NOTCH3-WT76 knockin strain, expression of the human NOTCH3 is blocked by an upstream loxP-flanked STOP sequence. Cre-mediated excision results in expression of human NOTCH3 and GFP targeted to the nucleus. Expression of NOTCH3 in vascular smooth muscle cells rescues the stroke susceptibility phenotype of Notch3 knockout mice.