型号：GM-J#036747 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#036704 -Cryorecovery

应用：Hic1CreERT2 mice have an IRES fused to a cre/ERT2 sequence inserted into the 3’ UTR of the Hic1 gene. This strain is useful for studying quiescent mesenchymal progenitor subpopulations and their role in tissue regeneration.

型号：GM-J#036703 -Cryorecovery

应用：Hic1f/f floxed mice have loxP sites flanking exon 2 of the Hic1 gene, which contains the translation initiation codon. These mice also contain a nuclear localized lacZ sequence downstream of the floxed region. This strain is useful for studying quiescent mesenchymal progenitor subpopulations and their role in tissue regeneration.

型号：GM-J#036689 -Available For Pre-Order

应用：MLR39 (CPV2/Cre) mice express Cre recombinase in the lens fiber cells of the eye starting at approximately embryonic day 12.5 (E12.5). Cre recombinase is also expressed in some retinal pigment epithelial (RPE) cells. A tyrosinase minigene leads to very faint pigmentation in the coat and retinal pigment epithelium of homozygotes.

型号：GM-J#036687 -Cryorecovery

应用：iPKR knock-in/knock-out mice were developed for cell type-specific drug-inducible protein synthesis inhibition (ciPSI). They are a spatiotemporally precise chemogenetic tool for rapidly and reversibly blocking cell-autonomous protein synthesis via phosphorylation of eIF2α (EIF2A). Expression of Eef1a1 is knocked out by the targeted insertion and homozygotes are not viable.

型号：GM-J#036670 -Available

应用：The double mutant Stock No. 036670 was created by breeding PolgAD257Aneo males from Stock No. 017341 (B6.129S7(Cg)-Polgtm1Prol/J) to Parkin knock-out females from Stock No. 006582 (B6.129S4-Prkntm1Shn/J).

型号：GM-J#036668 -Cryorecovery

应用：These Grpricre knock-in mice have an IRES-icre recombinase gene inserted immediately downstream of the stop codon in the 3' UTR of the X-linked gastrin releasing peptide receptor (Grpr) gene. This strain may useful for inducing efficient icre recombinase activity in neurons of the spinal cord dorsal horn.

型号：GM-J#036591 -Available

应用：Fcrls-2A-Cre knock-in mice have the endogenous Fcrl2 (formerly Fcrls) promoter/enhancer sequences directing expression of Cre recombinase. These mice are a Cre-lox tool allowing Cre recombination in Fcrl2-expressing cells/tissues (primarily microglia), and may be useful in studying neural development and neurodegenerative diseases.

型号：GM-J#036577 -Cryorecovery

应用：The Ptf1aCre-ERTM knock-in allele was designed to both abolish pancreas specific transcription factor, 1a (Ptf1a) gene function and express CreERTM fusion protein from the Ptf1a promoter/enhancer elements. PTF1A effects growth and lineage specification of pancreatic multipotent progenitor cells during development.

型号：GM-J#036564 -Available

应用：Nav1.8-Cre knock-in/knock-out mice carry Cre recombinase under the control of the Scn10a (sodium channel, voltage-gated, type X, alpha or Nav1.8) promoter. Cre expression is observed beginning at E14 in small diameter neurons in dorsal root, trigeminal and nodose ganglia. Mice heterozygous for the mutation can be used as a tool in pain behavior studies to delete floxed genes only in nociceptors.