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  • 型号:GM-J#036977 -Cryorecovery

    应用:Albino DbpKI;tyr conditional circadian reporter mice express firefly luciferase upon Cre recombinase-mediated excision of a loxP-flanked destabilized GFP (d2EGFP) cassette. This CRISPR/Cas9-generated knock-in allele enables the in vivo and ex vivo assessment of bioluminescent rhythms in specific cellular populations.

    2024-11-09 点击次数:0

    型号:GM-J#036976 -Cryorecovery

    应用:Krt5-CreERT2 knock-in mice have both endogenous gene and tamoxifen-inducible Cre recombinase expression directed to basal epithelial cells by the endogenous promoter/enhancer elements of the keratin 5 locus. These mice may be useful in generating conditional alleles for studying basal cells, cancer and epidermolysis bullosa.

    2024-11-09 点击次数:0

    型号:GM-J#036975 -Cryorecovery

    应用:The R26R-Confetti conditional allele has a CAG promoter followed by a floxed-STOP cassette and the Brainbow 2.1 construct all targeted into the Gt(ROSA)26Sor locus. The R26R-Confetti allele functions as a stochastic multicolor Cre recombinase reporter of multiple fluorescent proteins from a single genomic locus. These R26R-Confetti mice allow a way to label and distinguish individual / adjacent cells with nuclear localized, membrane-targeted, or cytoplasmic fluorescent proteins in cre recombined cells.

    2024-11-09 点击次数:0

    型号:GM-J#036955 -Available

    应用:C1ql2-Cre knock-in mice express Cre recombinase from the mouse C1ql2 (complement component 1, q subcomponent-like 2) promoter in C1ql2-expressing cells/tissues. These mice can be used to target anterior thalamic circuits, among other brain regions that also contain C1QL2‐expressing neurons, and may be useful in studies of autism, schizophrenia, and other neuropsychiatric disorders.

    2024-11-09 点击次数:0

    型号:GM-J#036942 -Available

    应用:Ager-CreERT2 mice carry a tamoxifen-inducible cre/ERT2 fusion gene inserted into the start codon of the advanced glycosylation end product-specific receptor (Ager) gene. Insertion of this fusion gene abolishes Ager gene expression.

    2024-11-09 点击次数:0

    型号:GM-J#036935 -Available For Pre-Order

    应用:SMMHC-CreERT2 transgenic mice allow sufficient Myh11-driven tamoxifen-inducible Cre expression in smooth muscle cells (SMCs).

    2024-11-09 点击次数:0

    型号:GM-J#036880 -Cryorecovery

    应用:LSL-FABP5 mice have the mouse Fabp5 cDNA and a YFP reporter behind a loxP-flanked STOP cassette. These mice allow for Cre-inducible over-expression of FABP5 protein and YFP in cells/tissues as determined by the Cre promoter and may be useful in the study of immunology and infectious disease.

    2024-11-09 点击次数:0

    型号:GM-J#036876 -Available

    应用:Avpr1bCre knock-in/knock-out mice have the endogenous arginine vasopressin receptor 1B promoter/enhancer sequences directing expression of Cre recombinase. These mice are a Cre-lox tool allowing Cre recombination in Avpr1b-expressing cells/tissues (including the caudate-putamen, olfactory bulb, and pyramidal neurons in the CA2 region of the hippocampus), and may be useful in studying memory, aggression, and regulation of the hypothalamic-pituitary-adrenal (HPA) axis.

    2024-11-09 点击次数:0

    型号:GM-J#036852 -Cryorecovery

    应用:Rab29- knock-out/lacZ reporter mice lack exon 4 of the Rab29 (RAB29, member RAS oncogene family) coding sequence. Homozygous null mice develop diminished locomotor behavior. This strain may be useful for studies of Parkinson's disease.

    2024-11-09 点击次数:0

    型号:GM-J#036851 -Available

    应用:Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

    2024-11-09 点击次数:0
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