型号：GM-J#067177-JAX -Cryorecovery

应用：R26-O2CreER(T2) mice express the oxygen-dependent degradation (ODD) domain from human HIF1A fused with an inducible Cre recombinase gene, all inserted into the ROSA26 locus. In combination with a loxP-flanked reporter, progeny can be used as a tamoxifen-inducible hypoxia-sensing model.

型号：GM-J#065813-JAX -Cryorecovery

应用：Sned1LacZ-Neo mice carry a knock-out first, conditional-ready, lacZ-tagged allele of the mouse Sned1 gene. Most homozygotes die within 2 days of being born. The rare knock-out survivors present severe craniofacial defects (shorter snouts, asymmetrical nasal cavities) and growth retardation.

型号：GM-J#050696-JAX -Cryorecovery

应用：Adh7 (alcohol dehydrogenase 7 (class IV) or Adh4) knock-out mice exhibit an impaired ability to metabolize a number of substrates including retinol (vitamin A), ethanol and dopamine.

型号：GM-J#043926-JAX -Cryorecovery

应用：Rosa26-LSL-dCas9 mice (Gt(ROSA)26Sortm1(CAG-dCas9-SunTag)Khk) are a Cre-inducible CRISPR/Cas9 activation (CRISPRa) tool for cell type specific gene activation in vivo.

型号：GM-J#043846-JAX -Cryorecovery

应用：ProkR2-Cre knock-in mice are designed to have codon optimized iCre recombinase expression directed to prokineticin receptor 2-expressing cells. These mice may be used to generate conditional mutations for studying gonadotropin-releasing hormone neuronal migration, olfactory bulb development, infertility, and Kallmann syndrome.

型号：GM-J#043796-JAX -Cryorecovery

应用：These BAC transgenic mice express Cre recombinase from the mouse Dcdc2a gene (doublecortin domain containing 2a). Recombination has been observed in ependymal cells lining the ventricle of the brain, the choroid plexus, and tanycytes in the third ventricle.

型号：GM-J#043695-JAX -Cryorecovery

应用：These BAC transgenic mice express Cre recombinase from the mouse Cbln1 (cerebellin 1 precursor protein) gene. Recombination has been observed in mitral neurons in the olfactory bulb, projection neurons in the entorhinal cortex and granule neurons in the cerebellum.

型号：GM-J#042277-JAX -Cryorecovery

应用：These Gcg-CreERT2 mice have Cre-ERT2 knocked into the 3' UTR region of the glucagon gene (Gcg). Inducible Cre expression is observed in pancreatic alpha cells and endocrine L cells.

型号：GM-J#041504-JAX -Cryorecovery

应用：These CRE3 transgenic mice express Cre recombinase under the control of the rat myosin light chain II ventricular (Mylpf or MLC2v) promoter beginning at E11.5 in the brain. This strain may be useful for generating conditional deletions in neurons and their progenitors.

型号：GM-J#039341 -Available For Registering Interest

应用：EKLF-CRE CRISPR-derived knock-in mice are designed to have T2A self-cleaving peptide fused to an iCre sequence inserted in-frame into the C-terminal of the Klf1 gene. The endogenous Klf1 promoter directs expression of iCre recombinase to tissues in the early developing embryo as well as in adult bone marrow. These mice are useful for studying and tracing the maturation of erythroid cells.