型号:GM-J#026662 -Available
应用:Mice harboring the PB-Cre4 transgene have the rat Pbsn, probasin, gene promoter directing expression of Cre recombinase to epithelial cells of the prostate.
型号:GM-J#026644 -Cryorecovery
应用:Lag3 KO mice are useful when studying cellular proliferation, activation, and homeostasis of T cells, and plays a role in Treg suppressive function.
型号:GM-J#026643 -Cryorecovery
应用:Exons 2-9 of the mouse Fas gene are flanked by loxP sites and tagged with human placental alkaline phosphatase (PLAP) in this conditional knockout/reporter allele. Following Cre-mediated recombination, everything except the secretion leader sequence of the gene is excised, and PLAP is expressed as a reporter for FAS.
型号:GM-J#026625 -Cryorecovery
应用:These Gcm1Cre mice express Cre recombinase under the control of the mouse Gcm1 gene promoter. Cre recombinase expression is detected in the syncytiotrophoblast layer 2 of the placenta. The transgene is imprinted and expressed only when inherited from the male.
型号:GM-J#026570 -Cryorecovery
应用:These Rosa26SNAPCaaX reporter mice conditionally express membrane-localized SNAP-tag from the Gt(ROSA)26Sor promoter upon cre-mediated excision of a floxed stop cassette. Cells expressing the SNAP-tag can be selectively labeled through treatment with benzylguanine (BG)-linked compounds, including synthetic fluorophores.
型号:GM-J#026525 -Cryorecovery
应用:Mfn2loxP floxed mice may be useful for generating conditional mutations in applications related to the study of mitochondrial fusion and morphology.
型号:GM-J#026516 -Not Available At Jax
应用:This strain has been discontinued. Please see the mixed genetic background version of this transgenic strain: STOCK Tg(Avil-icre/ERT2)AJwo/J (Stock No. 032027).
型号:GM-J#026512 -Cryorecovery
应用:TPOCreER transgenic mice express Cre-ERT2 under the direction of the human thyroid peroxidase promoter. They are useful for applications requiring tamoxifen-induced deletion of floxed sequences in the thyroid.
型号:GM-J#026294 -Cryorecovery
应用:ReaChR protein (a red-shifted channelrhodopsin) was tagged with mCitrine fluorescent protein and placed under the conditional control of the Gt(ROSA)26Sor promoter. Excision of a single loxP- flanked stop cassette enables fluorescent expression. As an optogenetic tool, this strain is useful for the selective activation and mapping of neuron populations.
型号:GM-J#026293 -Cryorecovery
应用:These ROSA26-LRRK2 (R1441C) mice allow cre-inducible expression of the familial Parkinson's disease-associated R1441C missense mutant form of LRRK2, and may be useful for studying Parkinson's disease pathogenesis and neurodegeneration.