型号：GM-J#032205 -Cryorecovery

应用：When these CAMPER, cAMP Encoded Reporter, mice are crossed with a Cre recombinase expressing strain, the floxed-STOP cassette is deleted and the Gt(ROSA)26Sor and CAG promoters drive expression of the TEpacVV cAMP sensor in the Cre-expressing cells. CAMPER mice allow selective cAMP concentration changes monitoring via FRET imaging in a tissue/cell-specific manner and may be useful in studies of G-protein-coupled receptors (GPCRs) responses.

型号：GM-J#032198 -Not Available At Jax

应用：This strain has been discontinued. Please search the JAXMice database for strains carrying the Pdpn promoter/gene.

型号：GM-J#032102 -Cryorecovery

应用：This Msx2-creERT2 mutant mouse strain, carrying a transgene with tamoxifen-inducible Cre recombinase under the control of the mouse Msx2 (msh homeobox 2) promoter and enhancers, may be useful for generating targeted mutants specific to the apical ectodermal ridge (AER) and its underlying mesenchyme of the developing limb, and in studies of bone development and BMP signaling.

型号：GM-J#032090-JAX -Cryorecovery

应用：These Park7 knockout mice exhibit non-progressive hypokinesia, progressive gait abnormalities, decreased grip strength, loss of body weight and may be useful in studies of Parkinson's disease.

型号：GM-J#032080 -Cryorecovery

应用：E8III-Cre transgenic mice have the E8III enhancer and promoter elements from CD8 antigen, alpha chain (Cd8a) gene driving expression of Cre recombinase. These mice may be useful for deletion of genes of interest in CD8a expressing thymocytes.

型号：GM-J#032068 -Cryorecovery

应用：Cre-mediated excision of a loxP-flanked stop cassette enables tissue-specific expression of the INDIA apoptosis reporter in these Rosa26LSL-INDIA mice. When aCasp3 (Casp3, caspase 3; a marker for apoptosis) cleaves a linker, the mNeonGreen and mRuby2 components of INDIA are separated, resulting in FRET loss and increased emission from mNeonGreen.

型号：GM-J#032052 -Cryorecovery

应用：KitMCM mice express MerCreMer (cre/Esr*) tamoxifen-inducible cre recombinase from the mouse Kit (KIT proto-oncogene receptor tyrosine kinase) promoter. These mice have been useful in tracing the lineage of Kit-expressing cardiac cells.

型号：GM-J#032051 -Cryorecovery

应用：These c-Kit Cre-ires-GFP mice, used to trace the lineage of Kit-expressing cardiac cells, express cre recombinase and nuclear-localize EGFP from the mouse Kit (also called c-Kit) promoter. Expression of the targeted Kit gene is eliminated.

型号：GM-J#032037-JAX -Cryorecovery

应用：These RCE:loxP mice harbor the R26R CAG-boosted EGFP (RCE) reporter allele with a loxP-flanked STOP cassette upstream of the enhanced green fluorescent protein (EGFP) gene. After removal of the loxP-flanked STOP cassette by cre-mediated recombination, EGFP reporter expression is directed to the cells/tissues dependent upon expression pattern of the promoter driving Cre recombinase.

型号：GM-J#032036-JAX -Cryorecovery

应用：These RCE:dual mice harbor the R26R CAG-boosted EGFP reporter allele with both a loxP-flanked STOP cassette and FRT-flanked STOP cassette upstream of the EGFP gene. After removal of the flanked STOP cassettes via cre- and Flp-mediated recombination, the EGFP reporter is expressed in cells/tissues where the expression patterns of the individual promoters driving Cre recombinase and FLP recombinase overlap.