型号:GM-J#006888 -Cryorecovery
应用:Cre recombinase expression in these mice is controlled by the zona pellucida 3 (Zp3) gene and is expressed in oocytes.
型号:GM-J#006881 -Cryorecovery
应用:These mice express Cre recombinase directed by endogenous Aqp2 promoter/enhancer elements. When bred to mice with a floxed gene of interest, Cre recombinase activity is observed in the collecting duct of kidney cells and in sperm of the testes. These mice may be used to generate conditional mutations for studying nephrology, physiology, metabolism, or type II diabetes.
型号:GM-J#006878 -Cryorecovery
应用:Mice homozygous for the transgelin knock-in allele (Taglntm2(cre)Yec or commonly referred to as SM22alpha-CreKI) exhibit Cre recombinase activity in adult smooth muscle cells and cardiac myocytes. These mice may be useful for Cre-lox technology applications in studying smooth muscle and cardiac gene function, as well as cardiovascular disease.
型号:GM-J#006823 -Available
应用:These Hualpha-Syn(A53T) transgenic mice display an age-dependent phenotype including progressive motor deficits, intraneuronal inclusion bodies and neuronal loss. This line may be useful for studying Parkinson's disease and other synucleinopathies associated with motor neuron loss and ubiquitinated inclusions in the brain stem and the spinal cord, Lewy bodies, and synaptic plasticity.
型号:GM-J#006785 -Available
应用:The CD19-Cre knock-in/knock-out allele has a Cre recombinase gene inserted into the first coding exon of the CD19 antigen gene; both abolishing endogenous Cd19 gene function and placing cre expression under the control of the endogenous Cd19 promoter/enhancer elements. Cre recombinase expression is directed at the earliest stages and throughout B-lymphocyte development and differentiation. Homozygous mice are also useful for studying B cell-deficiency.
型号:GM-J#006774 -Cryorecovery
应用:When these Col2CreERT mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in cartilage cells (both during embryogenesis and postnatally), as well as in other cell types that normally express the endogenous Type II collagen gene.
型号:GM-J#006721 -Cryorecovery
应用:This strain expresses a nuclear localized Cre recombinase in the subset of olfactory sensory neurons that would normally express Or2b4 (formerly Olfr124).
型号:GM-J#006677 -Cryorecovery
应用:These Cre recombinase mice are useful in studies to identify olfactory sensory neuronal development and topography in glomeruli in the olfactory bulb.
型号:GM-J#006668 -Cryorecovery
应用:These Cre recombinase mice are useful in studies to identify olfactory sensory neuronal lineage and topography in glomeruli in the olfactory bulb.
型号:GM-J#006663 -Cryorecovery
应用:The expression of Cre in these mice is driven by the promoter region of the rat neuron specific enolase (NSE or Eno2) gene and directed to neurons with expression in many tissue types.