型号:GM-J#007893 -Cryorecovery
应用:This strain expresses Cre recombinase from the endogenous Myf5 locus. When crossed with a strain containing loxP site flanked sequence of interest, Cre-mediated recombination results in tissue-specific deletion of the target, primarily in skeletal muscle and the dermis. This mutant mouse strain represents a model that may be useful in studies of skeletal development.
型号:GM-J#007845 -Not Available At Jax
应用:This strain has been discontinued. The Myf5tm3(cre)Sor targeted mutation has been cryopreserved under Stock No. 007893 B6.129S4-Myf5tm3(cre)Sor/J
型号:GM-J#007807 -Not Available At Jax
应用:In 2011, Stock No. 007807 at The Jackson Laboratory Repository was confirmed to harbor the expected Wnt1-Cre transgene, as well as the originally co-injected Wnt1-GAL4 transgene. Because it is redundant to Stock No. 003829, Stock No. 007807 has been terminated.
型号:GM-J#007742 -Available
应用:These smMHC(Myh11)/Cre/eGFP transgenic mice may be useful in studies utilizing "Cre-lox" technology or fluorescent protein expression in smooth muscle, especially separation of vascular myocytes from the surrounding cellular environment to isolate muscle specific adaptations or disease responses.
型号:GM-J#007684 -Cryorecovery
应用:These knock-in mice express a tamoxifen-inducible cre recombinase from the endogenous promoter/enhancer elements of the atonal homolog 1 (Drosophila) (Atoh1, also referred to as Math1) gene. When induced, cre activity is observed in neural progenitors of the cerebellar rhombic lip, dorsal hindbrain and spinal cord, as well as in inner-ear primordial. These mice may be useful in studying cerebellum development and fate mapping of Math1/Atoh1 cells.
型号:GM-J#007677 -Available
应用:GAD67-GFP (line G42) mice may be useful for fluorescent labeling of the Pv-expressing subset of GABAergic neurons, allowing reliable and efficient characterization of perisomatic innervation in vitro.
型号:GM-J#007676 -Available Now
应用:mT/mG (also called ROSAmT/mG) is a cell membrane-targeted, two-color fluorescent Cre-reporter allele. Prior to Cre recombination, cell membrane-localized tdTomato (mT) fluorescence expression is widespread in cells/tissues. Cre recombinase expressing cells (and future cell lineages derived from these cells) have cell membrane-localized EGFP (mG) fluorescence expression replacing the red fluorescence.
型号:GM-J#007673 -Cryorecovery
应用:These GAD67-GFP (line 3) mice may be useful for fluorescent labeling of neurons and studying the development, maturation, regulation, and functional integration of newborn neurons in adult hippocampus.
型号:GM-J#007610 -Cryorecovery
应用:These transgenic mice (“SLICK” for single-neuron labeling with inducible Cre-mediated knock-out) have a tamoxifen inducible Cre-mediated recombination system and Enhanced Yellow Fluorescent Protein driven by 2 bidirectional copies of the mouse thymus cell antigen 1 promoter. When crossed with a strain containing a loxP site flanked sequence of interest, the offspring are useful for generating tamoxifen-induced, Cre-mediated targeted neuron-specific deletions only in neurons that express Yellow Fluorescent Protein. The Donating Investigator reports that founder line V mice express the transgene sparsely in neurons of the central nervous system.
型号:GM-J#007606 -Cryorecovery
应用:These transgenic mice ("SLICK" for single-neuron labeling with inducible Cre-mediated knock-out) have a tamoxifen inducible Cre-mediated recombination system and Enhanced Yellow Fluorescent Protein driven by 2 bidirectional copies of the mouse thymus cell antigen 1 promoter. When crossed with a strain containing a loxP site flanked sequence of interest. The Donating Investigator reports that founder line A mice express the transgene in small subsets of motor neurons and dorsal root ganglion neurons.