型号：GM-J#006297 -Cryorecovery

应用：These transgenic mice harbor a Cre recombinase gene under the control of the rat neuron specific enolase (NSE or Eno2) gene, directing Cre recombinase activity to neurons with expression in many tissue types. These mice may also be useful in studies of spinal muscular atrophy (SMA) .

型号：GM-J#006244 -Cryorecovery

应用：Tetracycline inducible, tissue specific-targeted mutants can be generated by breeding hemizygotes of this strain with other transgenic mice that express transactivator proteins under the control of tissue-specific promoters.

型号：GM-J#006234 -Available

应用：These transgenic mice express Cre recombinase under the control of a tetracycline-responsive promoter element (TRE or tetO) and are an effective tool for generating inducible, tissue-specific, targeted mutants to study cell lineage during development. When bred with another transgenic mouse expressing reverse tetracycline-controlled transactivator protein (rtTA) or tetracycline-controlled transactivator protein (tTA), Cre mediated recombination in the resulting bitransgenic offspring can be regulated with the tetracycline analog, doxycycline.

型号：GM-J#006230 -Cryorecovery

应用：These mice express an interferon or synthetic double-stranded RNA inducible Cre recombinase. When induced, Cre recombinase activity is observed in hematopoietic tissue.

型号：GM-J#006224 -Cryorecovery

应用：Tetracycline inducible, tissue specific-targeted mutants can be generated by breeding hemizygotes of this strain with other transgenic mice that express transactivator proteins under the control of tissue-specific promoters.

型号：GM-J#006207 -Cryorecovery

应用：In these transgenic mice the L7/Pcp2 modified promoter directs tissue specific expression of cre in cerebellar Purkinje cells. A co-integrated GFP transgene results in GFP expression in the cerebellum.

型号：GM-J#006149 -Available

应用：These transgenic mice have the cre recombinase gene driven by the human alpha-skeletal actin (HSA or ACTA1) promoter. When bred with mice containing a loxP-flanked sequence of interest, Cre-mediated recombination will result in striated muscle-specific deletion of the flanked genome. These mice are useful in study of spinal muscular atrophy (SMA).

型号：GM-J#006148 -Available Now

应用：These R26-stop-EYFP mutant mice have a loxP-flanked STOP sequence followed by the Enhanced Yellow Fluorescent Protein gene (EYFP) inserted into the Gt(ROSA)26Sor locus. When bred to mice expressing Cre recombinase, the STOP sequence is deleted and EYFP expression is observed in the cre-expressing tissue(s) of the double mutant offspring. These mutant mice may be useful in monitoring the Cre expression in living tissues, and tracing the lineage of such cells in embryos, young, and adult mice at desired time points.

型号：GM-J#006143 -Cryorecovery

应用：Cre expression is driven in neurons of the postnatal cortex and hippocampus of hemizygous mice. These mice may be useful in studies of the nervous system, including Alzheimer's disease.

型号：GM-J#006139 -Cryorecovery

应用：These transgenic mice have the cre recombinase gene driven by the human alpha-skeletal actin (HSA or ACTA1) promoter. When bred with mice containing a loxP-flanked sequence of interest, Cre-mediated recombination will result in striated muscle-specific deletion of the flanked genome. These mice are useful in study of spinal muscular atrophy (SMA).