型号:GM-J#028287 -Cryorecovery
应用:The huLangerin-CreERT2 transgenic mice have tamoxifen-inducible Cre recombinase and human Langerin expression directed to Langerhans cells (LCs) by the human CD207 locus promoter/enhancer regions. This allows deletion of floxed sequences in fully-differentiated LCs.
型号:GM-J#028197 -Cryorecovery
应用:These Cd23-cre transgenic mice express cre under the control of the Fcer2a promoter and may be useful for generating conditional knockouts in B cells specific for studying B cell development and differentiation.
型号:GM-J#028196 -Available
应用:This Pax8cre knockin strain may be useful for generating conditional mutations for studying kidney and thyroid development.
型号:GM-J#028184 -Cryorecovery
应用:These floxed mutant mice possess loxP sites flanking exons 17 through 19 of the Tcf3 gene, and a FRT site flanked GFP-NEO cassette downstream of exon 19. This strain may be useful for generating conditional mutations in applications related to hematopoiesis, and as a reporter for E2A (Tcf3) expression.
型号:GM-J#028177 -Cryorecovery
应用:Tfr1fl/fl floxed mice possess loxP sites flanking exons 3-6 of the transferrin receptor gene. This strain may be useful for studying iron uptake.
型号:GM-J#028131 -Cryorecovery
应用:These Dbx1CreERT2 mice have Cre-ERT2 knocked into the 3’ UTR region of the developing brain homeobox 1 gene (Dbx1). This strain may be useful for mediating inducible cre recombination in Dbx1-expressing tissues, as well as for CNS neuronal progenitor subpopulation fate mapping.
型号:GM-J#028117 -Cryorecovery
应用:The Srd5a2G2aCE knock-in allele was designed to both abolish Srd5a2 gene expression and express EGFP and Cre-ERT2 proteins from the Srd5a2 promoter in the males reproductive tract and the ovary.
型号:GM-J#028116 -Cryorecovery
应用:The Wnt10bG2aCE knock-in allele was designed to both abolish Wnt10b gene expression and express EGFP and Cre-ERT2 proteins from the Wnt10b promoter in adult prostate and bladder.
型号:GM-J#028071 -Available
应用:This STOPflox R26-MetRS* knock-in strain enables genetically targeted (Cre-dependent) metabolic labeling of endogenous proteins in specific cell-types in vivo for subsequent imaging or purification and biochemical analysis.
型号:GM-J#028054 -Available
应用:These knock-in Sftpc-CreERT2 mice express a tamoxifen-inducible Cre recombinase from the endogenous promoter/enhancer elements of the Sftpc locus. When induced, Cre activity is observed in Type II alveolar cells.