型号：GM-J#028580 -Cryorecovery

应用：PV-2A-CreER knock-in mice express the CreERT2 fusion protein in parvalbumin positive neurons of the neocortex and cerebellum, as directed by the endogenous Pvalb promoter/enhancer elements.

型号：GM-J#028560 -Cryorecovery

应用：These SncaΔflox Rosa26-stop-lacZ reporter mice carry a knock out allele of the Snca gene and the Gt(ROSA)26Sortm1Sho Cre reporter allele. This strain may be useful for generating mutants in which Cre recombinase efficiency can be monitored for applications related to neurodegenerative synucleinopathies, such as Parkinson's disease and multiple system atrophy.

型号：GM-J#028559 -Cryorecovery

应用：These "SncaΔflox" knock-out mice mutant mice lack the first coding exon (exon II) of the Snca (synuclein, alpha) gene. This strain may be useful in studies related to neurodegenerative synucleinopathies, such as Parkinson's disease and multiple system atrophy.

型号：GM-J#028547 -Cryorecovery

应用：These Cyp17iCre transgenic mice have the mouse Cyp17a1 promoter driving codon optimized iCre recombinase expression in the ovarian theca/interstitial cells and Leydig cells in the testis.

型号：GM-J#028538 -Available

应用：These zDC-Cre knock-in mice express cre recombinase from the Zbtb46 promoter, enabling excision of loxP-flanked sequences in classical dendritic cells (cDCs).

型号：GM-J#028536 -Cryorecovery

应用：Ndnf-IRES2-dgCre-D knock-in mice have Cre recombinase expression directed by endogenous neuron-derived neurotrophic factor promoter/enhancer elements, without disrupting endogenous Ndnf expression. Although designed to be trimethoprim-inducible, the Cre recombinase activity is specific and efficient with or without TMP. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping in subgroups of neuronal populations (cortical layer 1, olfactory areas, hippocampal formation, striatum, midbrain and vascular cells).

型号：GM-J#028535 -Cryorecovery

应用：Ctgf-2A-dgCre-D knockin mice express a trimethoprim-inducible EGFP/Cre fusion gene directed by endogenous connective tissue growth factor promoter/enhancer elements, without disrupting endogenous Ctgf expression. When induced, Cre recombinase activity is restricted to layer 6b of the cortex and in restricted populations within the cortical subplate (e.g., endopiriform nucleus). These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping in these subgroups of brain tissues.

型号：GM-J#028534 -Available

应用：Slc17a8-IRES2-Cre-D knockin mice have Cre recombinase expression directed to Vglut3-expressing cells, without disrupting endogenous vesicular glutamate transporter 3 expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic synaptic vesicle trafficking.

型号：GM-J#028533 -Cryorecovery

应用：Cart-IRES2-Cre-D knockin mice have Cre recombinase expression directed to CART prepropeptide-expressing cells, without disrupting endogenous Cartpt expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping in subgroups of brain tissues (including cortex, cerebral nuclei, hypothalamus and midbrain) in regards to feeding, appetite and stress response, as well as gene regulation by cocaine and other drugs.

型号：GM-J#028532 -Available

应用：Calb1-IRES2-Cre-D knockin mice are designed to have Cre recombinase expression directed to calbindin 1-expressing cells in the hippocampus, striatum, thalamus, midbrain and cerebellum, without disrupting endogenous Calb1 expression. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to this calcium-binding protein.